About   Help   FAQ
Slc66a2 Gene Detail
Summary
  • Symbol
    Slc66a2
  • Name
    solute carrier family 66 member 2
  • Synonyms
    2310009N05Rik, 4933425L21Rik, 5730564E11Rik, C78974, Pqlc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914193
    NCBI Gene: 66943
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:80298458-80335940 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 53.37 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    404 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914193
 protein coding gene Chr18:80296507-80335940 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024594
 protein coding gene Chr18:81163892-81206897 (+)
A/J MGP_AJ_G0024561
 protein coding gene Chr18:77607688-77648992 (+)
AKR/J MGP_AKRJ_G0024532
 protein coding gene Chr18:79938836-79981184 (+)
BALB/cJ MGP_BALBcJ_G0024559
 protein coding gene Chr18:77793674-77834595 (+)
C3H/HeJ MGP_C3HHeJ_G0024328
 protein coding gene Chr18:80018213-80060715 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025006
 protein coding gene Chr18:83245425-83291910 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022437
 protein coding gene Chr18:76465361-76505716 (+)
CAST/EiJ MGP_CASTEiJ_G0023801
 protein coding gene Chr18:80349483-80392709 (+)
CBA/J MGP_CBAJ_G0024298
 protein coding gene Chr18:86290411-86336097 (+)
DBA/2J MGP_DBA2J_G0024428
 protein coding gene Chr18:77159158-77199014 (+)
FVB/NJ MGP_FVBNJ_G0024394
 protein coding gene Chr18:76480141-76519184 (+)
LP/J MGP_LPJ_G0024512
 protein coding gene Chr18:81037560-81076423 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024424
 protein coding gene Chr18:87540553-87585162 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025055
 protein coding gene Chr18:80074924-80116049 (+)
PWK/PhJ MGP_PWKPhJ_G0023546
 protein coding gene Chr18:77559676-77600280 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023352
 protein coding gene Chr18:80258507-80297496 (+)
WSB/EiJ MGP_WSBEiJ_G0023863
 protein coding gene Chr18:80029372-80071099 (+)



Homology
more
  • Human Ortholog
    SLC66A2, solute carrier family 66 member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC66A2, solute carrier family 66 member 2
  • Synonyms
    PQLC1
  • Links
    NCBI Gene ID: 80148
    neXtProt AC: NX_Q8N2U9
    UniProt: Q8N2U9

  • Chr Location
    18q23; chr18:79902420-79951657 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    782
  • Tissues
    10
  • cDNA Data
    103
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66943 NCBI Gene Model | MGI Sequence Detail 37483 C57BL/6J ±  kb
transcript NM_001164423 RefSeq | MGI Sequence Detail 3254 C57BL/6  
polypeptide Q80XM9 UniProt | EBI | MGI Sequence Detail 271 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 103
    cDNA 103

    Microarray probesets 6
Other
Accession IDs
less
MGI:1917916, MGI:1925388, MGI:2147406
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/12/2023
MGI 6.22 		The Jackson Laboratory