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Cops9 Gene Detail
Summary
  • Symbol
    Cops9
  • Name
    COP9 signalosome subunit 9
  • Synonyms
    1110002M09Rik, Myeov2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914165
    NCBI Gene: 66915
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:92564867-92569707 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 46.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    214 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914165
 protein coding gene Chr1:92564867-92569707 (-)
129S1/SvImJ ENSMUSG00200036660
 protein coding gene Chr1:89785240-89788705 (-)
A/J ENSMUSG00195027154
 protein coding gene Chr1:89344039-89347504 (-)
AKR/J ENSMUSG00220041788
 protein coding gene Chr1:89494412-89497877 (-)
BALB/cJ ENSMUSG00180014907
 protein coding gene Chr1:89656927-89660392 (-)
C3H/HeJ ENSMUSG00175001400
 protein coding gene Chr1:89539412-89542877 (-)
C57BL/6NJ ENSMUSG00215019493
 protein coding gene Chr1:89466596-89470061 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014438
 protein coding gene Chr1:85103209-85108020 (-)
CAST/EiJ ENSTCUG00005006638
 protein coding gene Chr1:89103486-89107003 (-)
CBA/J ENSMUSG00210011796
 protein coding gene Chr1:89384630-89388095 (-)
DBA/2J ENSMUSG00185013662
 protein coding gene Chr1:93857438-93860903 (-)
FVB/NJ ENSMUSG00205028963
 protein coding gene Chr1:88782646-88786111 (-)
JF1/MsJ ENSUMUG00000009661
 protein coding gene Chr1:92577688-92581255 (-)
LP/J ENSMUSG00230021916
 protein coding gene Chr1:93121384-93124849 (-)
NOD/ShiLtJ ENSMUSG00190027974
 protein coding gene Chr1:89424648-89428113 (-)
NZO/HlLtJ ENSMUSG00225001866
 protein coding gene Chr1:97016767-97020232 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010045314
 protein coding gene Chr1:91009037-91012450 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    COPS9, COP9 signalosome subunit 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COPS9, COP9 signalosome subunit 9
  • Synonyms
    CSNAP, MYEOV2
  • Links
    NCBI Gene ID: 150678
    UniProt: Q8WXC6

  • Chr Location
    2q37.3; chr2:240126548-240136807 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Cops9
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    77
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66915 NCBI Gene Model | MGI Sequence Detail 4841 C57BL/6J ±  kb
transcript NR_028108 RefSeq | MGI Sequence Detail 760 C57BL/6  
polypeptide Q3U898 UniProt | EBI | MGI Sequence Detail 57 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory