Ltap1 MGI Mouse Gene Detail - MGI:1914027 - lipid transport auxiliary protein 1

Symbol

Ltap1
Name

lipid transport auxiliary protein 1
Synonyms

4933434E20Rik, 5730552F22Rik

Feature Type

protein coding gene
IDs

MGI:1914027
NCBI Gene: 99650
Alliance

genome feature page
Transcription Start Sites

2 TSS

Sequence Map

Chr3:89958941-89969754 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 39.20 cM
Mapping Data

2 experiments

SNPs within 2kb

268 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914027	protein coding gene	Chr3:89958941-89970648 (+)
129S1/SvImJ	ENSMUSG00200036415	protein coding gene	Chr3:86814274-86825376 (+)
A/J	ENSMUSG00195051592	protein coding gene	Chr3:86829424-86840526 (+)
AKR/J	ENSMUSG00220046166	protein coding gene	Chr3:86783942-86795043 (+)
BALB/cJ	ENSMUSG00180043890	protein coding gene	Chr3:86921203-86932306 (+)
C3H/HeJ	ENSMUSG00175044854	protein coding gene	Chr3:86761992-86773094 (+)
C57BL/6NJ	ENSMUSG00215047293	protein coding gene	Chr3:87202047-87213149 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025223	protein coding gene	Chr3:82819234-82834687 (+)
CAST/EiJ	ENSTCUG00005043063	protein coding gene	Chr3:86281767-86292886 (+)
CBA/J	ENSMUSG00210045252	protein coding gene	Chr3:86899644-86910746 (+)
DBA/2J	ENSMUSG00185052077	protein coding gene	Chr3:87009640-87020743 (+)
FVB/NJ	ENSMUSG00205024072	protein coding gene	Chr3:85823635-85834737 (+)
JF1/MsJ	ENSUMUG00000048711	protein coding gene	Chr3:86621872-86632969 (+)
LP/J	ENSMUSG00230034039	protein coding gene	Chr3:89035518-89046623 (+)
NOD/ShiLtJ	ENSMUSG00190037845	protein coding gene	Chr3:87288238-87299343 (+)
NZO/HlLtJ	ENSMUSG00225008614	protein coding gene	Chr3:91793738-91804839 (+)
PWK/PhJ	ENSLUMG00010048597	protein coding gene	Chr3:86655650-86666738 (+)
SPRET/EiJ	no annotation
WSB/EiJ	ENSIUOG00005044795	protein coding gene	Chr3:87315093-87326194 (+)

Human Ortholog

LTAP1, lipid transport auxiliary protein 1

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

LTAP1, lipid transport auxiliary protein 1
Synonyms

C1orf43, HSPC012, NICE-3, NICE3, NS5ATP4, S863-3
Links

HGNC:29876

NCBI Gene ID: 25912

UniProt: Q9BWL3
Chr Location

1q21.3; chr1:154206668-154220681 (-) GRCh38

MGI Vertebrate Homology

Ltap1 stringent orthology
1 human;1 mouse;2 rat;1 zebrafish
HCOP

vertebrate homology predictions: LTAP1
Gene Tree

Ltap1

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References

1 with disease annotations

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Phenotype Summary

60 phenotypes from 1 allele in 1 genetic background
16 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

11
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

4
Radiation induced

1
Targeted

3
Genomic Mutations

2 involving Ltap1
Incidental Mutations

APF
Find Mice (IMSR)

30 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

14
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

78

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ltap1

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All Sequences

70
RefSeq

8
CCDS

CCDS17520.1, CCDS50967.1

Ensembl

ENSMUSG00000027942 (Evidence)
NCBI Gene

99650

			Length	Strain/Species	Flank
genomic	99650	NCBI Gene Model \| MGI Sequence Detail	10814	C57BL/6J	± kb
transcript	NM_001287087	RefSeq \| MGI Sequence Detail	1775	C57BL/6
polypeptide	NP_001274016	RefSeq \| MGI Sequence Detail	253	C57BL/6

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Protein Ontology

PR:000060173 lipid transport auxiliary protein 1

(term hierarchy)

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All nucleic 78

cDNA 78

Microarray probesets 7

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MGI:1917914, MGI:2139731, MGI:8328308

Summaries

All 42

Diseases 1

Gene Ontology 5

Phenotypes 16
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Ltap1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr30147	Chr3:89958844-89958872 (+)	-83 bp
Tssr30148	Chr3:89958937-89958943 (+)	-1 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/01/2026 MGI 6.24