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Zfp474 Gene Detail
Summary
  • Symbol
    Zfp474
  • Name
    zinc finger protein 474
  • Synonyms
    4933409D10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914008
    NCBI Gene: 66758
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:52748987-52772902 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 28.24 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1279 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914008
 protein coding gene Chr18:52748979-52772904 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024429
 protein coding gene Chr18:51739404-51763274 (+)
A/J MGP_AJ_G0024395
 protein coding gene Chr18:49749158-49772902 (+)
AKR/J MGP_AKRJ_G0024365
 protein coding gene Chr18:51137802-51164033 (+)
BALB/cJ MGP_BALBcJ_G0024395
 protein coding gene Chr18:49934768-49958507 (+)
C3H/HeJ MGP_C3HHeJ_G0024162
 protein coding gene Chr18:51275225-51299131 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024841
 protein coding gene Chr18:53487457-53514342 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022273
 protein coding gene Chr18:49540790-49564886 (+)
CAST/EiJ MGP_CASTEiJ_G0023636
 protein coding gene Chr18:51232752-51261007 (+)
CBA/J MGP_CBAJ_G0024132
 protein coding gene Chr18:55060626-55084369 (+)
DBA/2J MGP_DBA2J_G0024262
 protein coding gene Chr18:49457582-49481522 (+)
FVB/NJ MGP_FVBNJ_G0024229
 protein coding gene Chr18:48882630-48907551 (+)
LP/J MGP_LPJ_G0024347
 protein coding gene Chr18:51771437-51796172 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024259
 protein coding gene Chr18:56823027-56846941 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024888
 protein coding gene Chr18:51149847-51173756 (+)
PWK/PhJ MGP_PWKPhJ_G0023380
 protein coding gene Chr18:49454719-49478790 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023186
 protein coding gene Chr18:51330965-51357436 (+)
WSB/EiJ MGP_WSBEiJ_G0023699
 protein coding gene Chr18:51069391-51094691 (+)



Homology
more
  • Human Ortholog
    ZNF474, zinc finger protein 474
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF474, zinc finger protein 474
  • Links
    NCBI Gene ID: 133923
    neXtProt AC: NX_Q6S9Z5
    UniProt: Q6S9Z5

  • Chr Location
    5q23.2; chr5:122129546-122182658 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    8
  • cDNA Data
    11
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000046886 Ensembl Gene Model | MGI Sequence Detail 23916 C57BL/6J ±  kb
    transcript ENSMUST00000072666 Ensembl | MGI Sequence Detail 1930 Not Applicable  
    polypeptide ENSMUSP00000072453 Ensembl | MGI Sequence Detail 347 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 25
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory