About   Help   FAQ
Zfp474 Gene Detail
Summary
  • Symbol
    Zfp474
  • Name
    zinc finger protein 474
  • Synonyms
    4933409D10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914008
    NCBI Gene: 66758
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:52748987-52772902 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 28.24 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    841 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914008
 protein coding gene Chr18:52748979-52772904 (+)
129S1/SvImJ ENSMUSG00200029047
 protein coding gene Chr18:49774447-49798372 (+)
A/J ENSMUSG00195024184
 protein coding gene Chr18:49947632-49971375 (+)
AKR/J ENSMUSG00220020954
 protein coding gene Chr18:49892824-49916746 (+)
BALB/cJ ENSMUSG00180007338
 protein coding gene Chr18:50508196-50531937 (+)
C3H/HeJ ENSMUSG00175010900
 protein coding gene Chr18:50117081-50140998 (+)
C57BL/6NJ ENSMUSG00215006175
 protein coding gene Chr18:49470659-49494577 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022273
 protein coding gene Chr18:49540790-49564886 (+)
CAST/EiJ ENSTCUG00005013045
 protein coding gene Chr18:49334543-49358451 (+)
CBA/J ENSMUSG00210022437
 protein coding gene Chr18:50050576-50074321 (+)
DBA/2J ENSMUSG00185027617
 protein coding gene Chr18:49970529-49994272 (+)
FVB/NJ ENSMUSG00205013850
 protein coding gene Chr18:49411882-49435629 (+)
JF1/MsJ ENSUMUG00000024664
 protein coding gene Chr18:49882891-49906389 (+)
LP/J ENSMUSG00230011091
 protein coding gene Chr18:51960525-51984450 (+)
NOD/ShiLtJ ENSMUSG00190026809
 protein coding gene Chr18:49668280-49692200 (+)
NZO/HlLtJ ENSMUSG00225033909
 protein coding gene Chr18:51874302-51898223 (+)
PWK/PhJ ENSLUMG00010020751
 protein coding gene Chr18:50044084-50067734 (+)
SPRET/EiJ ENSMSPG00010012103
 protein coding gene Chr18:50395939-50397697 (+)
WSB/EiJ ENSIUOG00005008986
 protein coding gene Chr18:49573938-49597853 (+)



Homology
more
  • Human Ortholog
    ZNF474, zinc finger protein 474
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF474, zinc finger protein 474
  • Links
    NCBI Gene ID: 133923
    UniProt: Q6S9Z5

  • Chr Location
    5q23.2; chr5:122129546-122182658 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a knock-out allele are fertile and exhibit normal testis gross appearance, normal testis and epididymis histology and germ cell number, and normal sperm morphology and motility.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    612
  • Tissues
    8
  • cDNA Data
    11
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000046886 Ensembl Gene Model | MGI Sequence Detail 23916 C57BL/6J ±  kb
    transcript ENSMUST00000209270 Ensembl | MGI Sequence Detail 2113 Not Applicable  
    polypeptide ENSMUSP00000147873 Ensembl | MGI Sequence Detail 347 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 2
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:385753 Qiu Y, et al., CRISPR/Cas9-mediated Genome-editing Reveals 10 Testis-enriched Genes and One Non-testis-enriched Gene are Dispensable for Male Fecundity in Mice. Andrology. 2025 Nov 10;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory