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Ndufaf3 Gene Detail
Summary
  • Symbol
    Ndufaf3
  • Name
    NADH:ubiquinone oxidoreductase complex assembly factor 3
  • Synonyms
    4733401H18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913956
    NCBI Gene: 66706
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:108442786-108444635 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.50 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    8 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913956
 protein coding gene Chr9:108442736-108444635 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035305
 protein coding gene Chr9:110533243-110534296 (-)
A/J MGP_AJ_G0035284
 protein coding gene Chr9:106482110-106483163 (-)
AKR/J MGP_AKRJ_G0035216
 protein coding gene Chr9:109151204-109152257 (-)
BALB/cJ MGP_BALBcJ_G0035278
 protein coding gene Chr9:106177574-106178627 (-)
C3H/HeJ MGP_C3HHeJ_G0034988
 protein coding gene Chr9:109552552-109553605 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035798
 protein coding gene Chr9:113547926-113548979 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032696
 protein coding gene Chr9:103909932-103911688 (-)
CAST/EiJ MGP_CASTEiJ_G0034299
 protein coding gene Chr9:109510245-109511591 (-)
CBA/J MGP_CBAJ_G0034956
 protein coding gene Chr9:117554125-117555180 (-)
DBA/2J MGP_DBA2J_G0035117
 protein coding gene Chr9:105941075-105942128 (-)
FVB/NJ MGP_FVBNJ_G0035065
 protein coding gene Chr9:104702742-104704258 (-)
LP/J MGP_LPJ_G0035193
 protein coding gene Chr9:110727793-110728846 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035104
 protein coding gene Chr9:119126227-119127280 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035819
 protein coding gene Chr9:109429999-109431052 (-)
PWK/PhJ MGP_PWKPhJ_G0034006
 protein coding gene Chr9:106266173-106268071 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033841
 protein coding gene Chr9:109492750-109493805 (-)
WSB/EiJ MGP_WSBEiJ_G0034420
 protein coding gene Chr9:109311440-109313256 (-)



Homology
more
  • Human Ortholog
    NDUFAF3, NADH:ubiquinone oxidoreductase complex assembly factor 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFAF3, NADH:ubiquinone oxidoreductase complex assembly factor 3
  • Synonyms
    2P1, C3orf60, E3-3, MC1DN18
  • Links
    NCBI Gene ID: 25915
    neXtProt AC: NX_Q9BU61
    UniProt: Q9BU61

  • Chr Location
    3p21.31; chr3:49020475-49023495 (+)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with human NDUFAF3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    1
  • cDNA Data
    78
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66706 NCBI Gene Model | MGI Sequence Detail 1850 C57BL/6J ±  kb
transcript NM_023247 RefSeq | MGI Sequence Detail 1453 C57BL/6  
polypeptide Q9JKL4 UniProt | EBI | MGI Sequence Detail 185 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032370 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3
    (term hierarchy)
  • InterPro Domains
    IPR036748 MTH938-like superfamily
    IPR034095 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3
    IPR007523 NDUFAF3/Mth938 domain-containing protein
Molecular
Reagents
less
  • All nucleic 78
    cDNA 78

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/31/2023
MGI 6.22 		The Jackson Laboratory