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Chmp7 Gene Detail
Summary
  • Symbol
    Chmp7
  • Name
    charged multivesicular body protein 7
  • Synonyms
    4930596K11Rik, 6330407G04Rik, CHMP family, member 7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913922
    NCBI Gene: 105513
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:69954449-69969990 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 36.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    113 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913922
 protein coding gene Chr14:69954428-69970019 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021524
 protein coding gene Chr14:64295757-64317667 (-)
A/J MGP_AJ_G0021483
 protein coding gene Chr14:62972176-62988704 (-)
AKR/J MGP_AKRJ_G0021459
 protein coding gene Chr14:64856922-64872470 (-)
BALB/cJ MGP_BALBcJ_G0021489
 protein coding gene Chr14:62732559-62748673 (-)
C3H/HeJ MGP_C3HHeJ_G0021266
 protein coding gene Chr14:64578951-64596526 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021928
 protein coding gene Chr14:67205005-67220575 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019468
 protein coding gene Chr14:60818464-60832489 (-)
CAST/EiJ MGP_CASTEiJ_G0020783
 protein coding gene Chr14:61130777-61148004 (-)
CBA/J MGP_CBAJ_G0021233
 protein coding gene Chr14:69306860-69325040 (-)
DBA/2J MGP_DBA2J_G0021356
 protein coding gene Chr14:62356767-62372467 (-)
FVB/NJ MGP_FVBNJ_G0021335
 protein coding gene Chr14:61777292-61793147 (-)
LP/J MGP_LPJ_G0021426
 protein coding gene Chr14:65565423-65582279 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021364
 protein coding gene Chr14:68245324-68262132 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021951
 protein coding gene Chr14:64119073-64138558 (-)
PWK/PhJ MGP_PWKPhJ_G0020527
 protein coding gene Chr14:59112351-59125773 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020360
 protein coding gene Chr14:60053225-60068286 (-)
WSB/EiJ MGP_WSBEiJ_G0020836
 protein coding gene Chr14:64421415-64440789 (-)



Homology
more
  • Human Ortholog
    CHMP7, charged multivesicular body protein 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHMP7, charged multivesicular body protein 7
  • Links
    NCBI Gene ID: 91782
    neXtProt AC: NX_Q8WUX9
    UniProt: Q8WUX9

  • Chr Location
    8p21.3; chr8:23243637-23262000 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    71
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    747
  • Tissues
    39
  • cDNA Data
    111
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034190 Ensembl Gene Model | MGI Sequence Detail 15542 C57BL/6J ±  kb
transcript ENSMUST00000036381 Ensembl | MGI Sequence Detail 2649 Not Applicable  
polypeptide ENSMUSP00000047700 Ensembl | MGI Sequence Detail 451 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 115
    cDNA 113
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1923217, MGI:2145652, MGI:2145833
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:339600 Hermosilla Aguayo V, et al., ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory