Cmc2 MGI Mouse Gene Detail - MGI:1913781 - C-X9-C motif containing 2

Symbol

Cmc2
Name

C-X9-C motif containing 2
Synonyms

1110046L09Rik, 2310061C15Rik

Feature Type

protein coding gene
IDs

MGI:1913781
NCBI Gene: 66531
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr8:117615424-117648194 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 8, 63.28 cM, cytoband E1
Mapping Data

2 experiments

SNPs within 2kb

145 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913781	protein coding gene	Chr8:117615424-117671061 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0034165	protein coding gene	Chr8:120010879-120041289 (-)
A/J	MGP_AJ_G0034145	protein coding gene	Chr8:115134919-115160623 (-)
AKR/J	MGP_AKRJ_G0034072	protein coding gene	Chr8:118480373-118507865 (-)
BALB/cJ	MGP_BALBcJ_G0034139	protein coding gene	Chr8:115331179-115357406 (-)
C3H/HeJ	MGP_C3HHeJ_G0033850	protein coding gene	Chr8:119206411-119231824 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0034659	protein coding gene	Chr8:124087107-124118875 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031601	protein coding gene	Chr8:108068186-108092243 (-)
CAST/EiJ	MGP_CASTEiJ_G0033177	protein coding gene	Chr8:119014088-119047585 (-)
CBA/J	MGP_CBAJ_G0033823	protein coding gene	Chr8:128565054-128599800 (-)
DBA/2J	MGP_DBA2J_G0033979	protein coding gene	Chr8:114355707-114388721 (-)
FVB/NJ	MGP_FVBNJ_G0033922	protein coding gene	Chr8:113337437-113363887 (-)
LP/J	MGP_LPJ_G0034068	protein coding gene	Chr8:120145752-120173663 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0033969	protein coding gene	Chr8:131162337-131194184 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034677	protein coding gene	Chr8:118574247-118601907 (-)
PWK/PhJ	MGP_PWKPhJ_G0032879	protein coding gene	Chr8:114061435-114087615 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0032719	protein coding gene	Chr8:117260228-117288496 (-)
WSB/EiJ	MGP_WSBEiJ_G0033293	protein coding gene	Chr8:119288088-119314553 (-)

Human Ortholog

CMC2, C-X9-C motif containing 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CMC2, C-X9-C motif containing 2
Synonyms

2310061C15Rik, C16orf61, DC13
Links

HGNC:24447

NCBI Gene ID: 56942

neXtProt AC: NX_Q9NRP2

UniProt: Q9NRP2
Chr Location

16q23.2; chr16:80966448-81020270 (-) GRCh38

MGI Vertebrate Homology

Cmc2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CMC2
Gene Tree

Cmc2

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Phenotype Summary

5 phenotype references

All Mutations and Alleles

16
Gene trapped

15
Targeted

1
Find Mice (IMSR)

16 strains or lines available

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All GO Annotations

3
GO References

3

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

707
Tissues

1
cDNA Data

56
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase cmc2

ZFIN cmc2

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All Sequences

56
RefSeq

6
UniProt

5
CCDS

CCDS40489.1

Ensembl

ENSMUSG00000014633 (Evidence)
NCBI Gene

66531

			Length	Strain/Species	Flank
genomic	ENSMUSG00000014633	Ensembl Gene Model \| MGI Sequence Detail	32771	C57BL/6J	± kb
transcript	ENSMUST00000128304	Ensembl \| MGI Sequence Detail	394	Not Applicable
polypeptide	ENSMUSP00000120919	Ensembl \| MGI Sequence Detail	99	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000032372 COX assembly mitochondrial protein 2 homolog

(term hierarchy)
InterPro Domains

IPR013892 Cytochrome c oxidase biogenesis protein Cmc1-like

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All nucleic 56

cDNA 56

Microarray probesets 7

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MGI:1916061

Summaries

All 30

Developmental Gene Expression 1

Gene Ontology 3

Phenotypes 5
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

TSS for Cmc2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr83083	Chr8:117648147-117648190 (-)	25 bp
Tssr83082	Chr8:117648117-117648131 (-)	70 bp
Tssr83081	Chr8:117621503-117621514 (-)	26,685 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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