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Sys1 Gene Detail
Summary
  • Symbol
    Sys1
  • Name
    SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
  • Synonyms
    2610042O14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913710
    NCBI Gene: 66460
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164298884-164321558 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.16 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    700 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913710
 protein coding gene Chr2:164297736-164322141 (+)
129S1/SvImJ ENSMUSG00200016212
 protein coding gene Chr2:161184055-161210010 (+)
A/J ENSMUSG00195017500
 protein coding gene Chr2:161517792-161542287 (+)
AKR/J ENSMUSG00220013477
 protein coding gene Chr2:160840310-160871289 (+)
BALB/cJ ENSMUSG00180047055
 protein coding gene Chr2:160971560-160996061 (+)
C3H/HeJ ENSMUSG00175045129
 protein coding gene Chr2:161717776-161743851 (+)
C57BL/6NJ ENSMUSG00215019271
 protein coding gene Chr2:161168838-161193375 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024645
 protein coding gene Chr2:156396876-156418460 (+)
CAST/EiJ ENSTCUG00005044179
 protein coding gene Chr2:160088323-160112828 (+)
CBA/J ENSMUSG00210016072
 protein coding gene Chr2:161652245-161676737 (+)
DBA/2J ENSMUSG00185048430
 protein coding gene Chr2:161384974-161409450 (+)
FVB/NJ ENSMUSG00205033663
 protein coding gene Chr2:160405837-160431909 (+)
JF1/MsJ ENSUMUG00000012715
 protein coding gene Chr2:161028329-161052746 (+)
LP/J ENSMUSG00230040616
 protein coding gene Chr2:162945158-162971112 (+)
NOD/ShiLtJ ENSMUSG00190035853
 protein coding gene Chr2:161057078-161081570 (+)
NZO/HlLtJ ENSMUSG00225052628
 protein coding gene Chr2:170947306-170973380 (+)
PWK/PhJ ENSLUMG00010039649
 protein coding gene Chr2:160933271-160955857 (+)
SPRET/EiJ ENSMSPG00010033366
 protein coding gene Chr2:163700700-163712280 (+)
WSB/EiJ ENSIUOG00005045295
 protein coding gene Chr2:160778084-160802592 (+)



Homology
more
  • Human Ortholog
    SYS1, SYS1 golgi trafficking protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYS1, SYS1 golgi trafficking protein
  • Synonyms
    C20orf169, dJ453C12.4, dJ453C12.4.1
  • Links
    NCBI Gene ID: 90196
    UniProt: Q8N2H4

  • Chr Location
    20q13.12; chr20:45359977-45376798 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    23
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045503 Ensembl Gene Model | MGI Sequence Detail 22675 C57BL/6J ±  kb
transcript ENSMUST00000109352 Ensembl | MGI Sequence Detail 2001 Not Applicable  
polypeptide ENSMUSP00000104976 Ensembl | MGI Sequence Detail 156 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 10
Other
Accession IDs
less
MGI:2138874, MGI:2139531
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:362374 Zuo H, et al., SYISL Knockout Promotes Embryonic Muscle Development of Offspring by Modulating Maternal Gut Microbiota and Fetal Myogenic Cell Dynamics. Adv Sci (Weinh). 2025 Feb;12(6):e2410953
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory