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Ndufa12 Gene Detail
Summary
  • Symbol
    Ndufa12
  • Name
    NADH:ubiquinone oxidoreductase subunit A12
  • Synonyms
    2410011G03Rik, MGC:7999
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913664
    NCBI Gene: 66414
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:94034897-94057302 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 48.83 cM, cytoband F
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    322 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913664
 protein coding gene Chr10:94034582-94057305 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017662
 protein coding gene Chr10:95669234-95693645 (+)
A/J MGP_AJ_G0017641
 protein coding gene Chr10:92312336-92333932 (+)
AKR/J MGP_AKRJ_G0017599
 protein coding gene Chr10:94954815-94977050 (+)
BALB/cJ MGP_BALBcJ_G0017604
 protein coding gene Chr10:92591125-92613107 (+)
C3H/HeJ MGP_C3HHeJ_G0017427
 protein coding gene Chr10:94950254-94971649 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018061
 protein coding gene Chr10:98822288-98851552 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015742
 protein coding gene Chr10:87897042-87918763 (+)
CAST/EiJ MGP_CASTEiJ_G0016992
 protein coding gene Chr10:94955185-94982375 (+)
CBA/J MGP_CBAJ_G0017396
 protein coding gene Chr10:102913159-102942260 (+)
DBA/2J MGP_DBA2J_G0017502
 protein coding gene Chr10:91406985-91430119 (+)
FVB/NJ MGP_FVBNJ_G0017494
 protein coding gene Chr10:90647199-90668013 (+)
LP/J MGP_LPJ_G0017576
 protein coding gene Chr10:96272496-96302615 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017525
 protein coding gene Chr10:104167518-104188489 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018098
 protein coding gene Chr10:94861268-94883635 (+)
PWK/PhJ MGP_PWKPhJ_G0016773
 protein coding gene Chr10:91503400-91525407 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016561
 protein coding gene Chr10:93667536-93689343 (+)
WSB/EiJ MGP_WSBEiJ_G0017051
 protein coding gene Chr10:94824291-94847886 (+)



Homology
more
  • Human Ortholog
    NDUFA12, NADH:ubiquinone oxidoreductase subunit A12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFA12, NADH:ubiquinone oxidoreductase subunit A12
  • Synonyms
    B17.2, DAP13, MC1DN23
  • Links
    NCBI Gene ID: 55967
    neXtProt AC: NX_Q9UI09
    UniProt: Q9UI09

  • Chr Location
    12q22; chr12:94895297-95003748 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human NDUFA12 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    2
  • Targeted
    1
  • Transposon induced
    1
  • Genomic Mutations
    2 involving Ndufa12
  • Find Mice (IMSR)
    15 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    8
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    13
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66414 NCBI Gene Model | MGI Sequence Detail 22406 C57BL/6J ±  kb
transcript NM_001364691 RefSeq | MGI Sequence Detail 1042 C57BL/6  
polypeptide Q7TMF3 UniProt | EBI | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 5
Other
Accession IDs
less
MGI:2141156
References
more
  • Summaries
    All 46
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:317438 Sheng X, et al., The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals. EBioMedicine. 2021 Dec 30;75:103790
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory