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Knop1 Gene Detail
Summary
  • Symbol
    Knop1
  • Name
    lysine rich nucleolar protein 1
  • Synonyms
    2310008H09Rik, Tsg118
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913606
    NCBI Gene: 66356
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:118441440-118454907 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 63.66 cM, cytoband F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    470 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913606
 protein coding gene Chr7:118441440-118455224 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032905
 protein coding gene Chr7:122722767-122737658 (-)
A/J MGP_AJ_G0032888
 protein coding gene Chr7:119586798-119600840 (-)
AKR/J MGP_AKRJ_G0032820
 protein coding gene Chr7:122645043-122659075 (-)
BALB/cJ MGP_BALBcJ_G0032893
 protein coding gene Chr7:119301640-119316785 (-)
C3H/HeJ MGP_C3HHeJ_G0032603
 protein coding gene Chr7:122543381-122557291 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033399
 protein coding gene Chr7:127600811-127614842 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030371
 protein coding gene Chr7:121021512-121035567 (-)
CAST/EiJ MGP_CASTEiJ_G0031931
 protein coding gene Chr7:114309607-114323671 (-)
CBA/J MGP_CBAJ_G0032576
 protein coding gene Chr7:131878214-131894589 (-)
DBA/2J MGP_DBA2J_G0032728
 protein coding gene Chr7:117623689-117638000 (-)
FVB/NJ MGP_FVBNJ_G0032681
 protein coding gene Chr7:117465684-117479716 (-)
LP/J MGP_LPJ_G0032822
 protein coding gene Chr7:124176862-124192453 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032713
 protein coding gene Chr7:133350326-133364358 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033419
 protein coding gene Chr7:121648924-121662953 (-)
PWK/PhJ MGP_PWKPhJ_G0031639
 protein coding gene Chr7:110529093-110543021 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031486
 protein coding gene Chr7:108369569-108383360 (-)
WSB/EiJ MGP_WSBEiJ_G0032044
 protein coding gene Chr7:122534125-122548297 (-)



Homology
more
  • Human Ortholog
    KNOP1, lysine rich nucleolar protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KNOP1, lysine rich nucleolar protein 1
  • Synonyms
    101F10.1, C16orf88, FAM191A, TSG118
  • Links
    NCBI Gene ID: 400506
    UniProt: Q1ED39

  • Chr Location
    16p12.3; chr16:19701937-19718235 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    4
  • cDNA Data
    171
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66356 NCBI Gene Model | MGI Sequence Detail 13468 C57BL/6J ±  kb
    transcript NM_023197 RefSeq | MGI Sequence Detail 5073 C57BL/6  
    polypeptide Q9Z2Q2 UniProt | EBI | MGI Sequence Detail 478 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 172
      cDNA 171
      Other 1

      Microarray probesets 6
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 3
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory