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Scp2d1 Gene Detail
Summary
  • Symbol
    Scp2d1
  • Name
    SCP2 sterol-binding domain containing 1
  • Synonyms
    1700010M22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913578
    NCBI Gene: 66328
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr2:144665586-144666335 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 71.02 cM, cytoband H1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913578
 protein coding gene Chr2:144665576-144666335 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026592
 protein coding gene Chr2:148936002-148936761 (+)
A/J MGP_AJ_G0026556
 protein coding gene Chr2:142912879-142913638 (+)
AKR/J MGP_AKRJ_G0026530
 protein coding gene Chr2:147014037-147014796 (+)
BALB/cJ MGP_BALBcJ_G0026568
 protein coding gene Chr2:143348476-143349235 (+)
C3H/HeJ MGP_C3HHeJ_G0026311
 protein coding gene Chr2:147560037-147560796 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027013
 protein coding gene Chr2:153387050-153387809 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024390
 protein coding gene Chr2:137075956-137076715 (+)
CAST/EiJ MGP_CASTEiJ_G0025772
 protein coding gene Chr2:147890431-147891190 (+)
CBA/J MGP_CBAJ_G0026291
 protein coding gene Chr2:158984616-158985375 (+)
DBA/2J MGP_DBA2J_G0026425
 protein coding gene Chr2:142181265-142182024 (+)
FVB/NJ MGP_FVBNJ_G0026389
 protein coding gene Chr2:140760736-140761495 (+)
LP/J MGP_LPJ_G0026529
 protein coding gene Chr2:149084752-149085511 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026409
 protein coding gene Chr2:163180146-163180905 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027068
 protein coding gene Chr2:147008253-147009012 (+)
PWK/PhJ MGP_PWKPhJ_G0028139
 protein coding gene Chr5:14621579-14624094 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027972
 protein coding gene Chr5:14923480-14924151 (+)
WSB/EiJ MGP_WSBEiJ_G0025845
 protein coding gene Chr2:148017523-148018282 (+)



Homology
more
  • Human Ortholog
    SCP2D1, SCP2 sterol binding domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCP2D1, SCP2 sterol binding domain containing 1
  • Synonyms
    C20orf79, dJ1068E13.2, HSD22
  • Links
    NCBI Gene ID: 140856
    neXtProt AC: NX_Q9UJQ7
    UniProt: Q9UJQ7

  • Chr Location
    20p11.23; chr20:18813783-18814378 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Scp2d1
  • Find Mice (IMSR)
    9 strains or lines available
Male mice homozygous for a null allele exhibit normal fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66328 NCBI Gene Model | MGI Sequence Detail 750 C57BL/6J ±  kb
transcript NM_025490 RefSeq | MGI Sequence Detail 750 Not Specified  
polypeptide Q9DAH1 UniProt | EBI | MGI Sequence Detail 156 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory