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Ier3ip1 Gene Detail
Summary
  • Symbol
    Ier3ip1
  • Name
    immediate early response 3 interacting protein 1
  • Synonyms
    1110057H19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913441
    NCBI Gene: 66191
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:77017723-77029310 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 18, 51.98 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    394 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913441
protein coding gene Chr18:77017713-77029310 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024569
protein coding gene Chr18:77656161-77670014 (+)
A/J MGP_AJ_G0024536
protein coding gene Chr18:74257768-74269346 (+)
AKR/J MGP_AKRJ_G0024507
protein coding gene Chr18:76462657-76474233 (+)
BALB/cJ MGP_BALBcJ_G0024535
protein coding gene Chr18:74485313-74496892 (+)
C3H/HeJ MGP_C3HHeJ_G0024304
protein coding gene Chr18:76570784-76582384 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024982
protein coding gene Chr18:79702223-79713843 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022412
protein coding gene Chr18:73289123-73300929 (+)
CAST/EiJ MGP_CASTEiJ_G0023776
protein coding gene Chr18:76824076-76838284 (+)
CBA/J MGP_CBAJ_G0024273
protein coding gene Chr18:82504903-82516495 (+)
DBA/2J MGP_DBA2J_G0024403
protein coding gene Chr18:73847633-73859226 (+)
FVB/NJ MGP_FVBNJ_G0024369
protein coding gene Chr18:73201294-73212894 (+)
LP/J MGP_LPJ_G0024487
protein coding gene Chr18:77535027-77548499 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024399
protein coding gene Chr18:83791644-83803231 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025030
protein coding gene Chr18:76613199-76624781 (+)
PWK/PhJ MGP_PWKPhJ_G0023521
protein coding gene Chr18:74255842-74267666 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023325
protein coding gene Chr18:76811689-76823201 (+)
WSB/EiJ MGP_WSBEiJ_G0023840
protein coding gene Chr18:76579564-76591168 (+)



Homology
more
  • Human Ortholog
    IER3IP1, immediate early response 3 interacting protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IER3IP1, immediate early response 3 interacting protein 1
  • Synonyms
    HSPC039, MEDS, PRO2309
  • Links
    NCBI Gene ID: 51124
    neXtProt AC: NX_Q9Y5U9
    UniProt: Q9Y5U9

  • Chr Location
    18q21.1; chr18:47152834-47176364 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotypes from 2 alleles in 3 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66191 NCBI Gene Model | MGI Sequence Detail 11588 C57BL/6J ±  kb
    transcript NM_025409 RefSeq | MGI Sequence Detail 1404 C57BL/6  
    polypeptide Q9CR20 UniProt | EBI | MGI Sequence Detail 82 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 9
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2145319, MGI:2145320, MGI:2147249, MGI:2147332
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    07/05/2024
    MGI 6.24
    The Jackson Laboratory