Ogfod3 MGI Mouse Gene Detail - MGI:1913429 - 2-oxoglutarate and iron-dependent oxygenase domain containing 3

Symbol

Ogfod3
Name

2-oxoglutarate and iron-dependent oxygenase domain containing 3
Synonyms

1110031I02Rik

Feature Type

protein coding gene
IDs

MGI:1913429
NCBI Gene: 66179
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr11:121068419-121095474 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 85.04 cM, cytoband E2
Mapping Data

2 experiments

SNPs within 2kb

116 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913429	protein coding gene	Chr11:121068417-121095537 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0019541	protein coding gene	Chr11:125715249-125743212 (-)
A/J	MGP_AJ_G0019508	protein coding gene	Chr11:120101817-120124037 (-)
AKR/J	MGP_AKRJ_G0019478	protein coding gene	Chr11:123736884-123763876 (-)
BALB/cJ	MGP_BALBcJ_G0019483	protein coding gene	Chr11:120468050-120495493 (-)
C3H/HeJ	MGP_C3HHeJ_G0019289	protein coding gene	Chr11:124060382-124089547 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0019932	protein coding gene	Chr11:129528907-129555678 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017557	protein coding gene	Chr11:117080643-117110590 (-)
CAST/EiJ	MGP_CASTEiJ_G0018843	protein coding gene	Chr11:125561923-125593952 (-)
CBA/J	MGP_CBAJ_G0019260	protein coding gene	Chr11:134564444-134591182 (-)
DBA/2J	MGP_DBA2J_G0019373	protein coding gene	Chr11:119466465-119494888 (-)
FVB/NJ	MGP_FVBNJ_G0019364	protein coding gene	Chr11:119183258-119211007 (-)
LP/J	MGP_LPJ_G0019444	protein coding gene	Chr11:125991952-126019536 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019397	protein coding gene	Chr11:133375238-133402793 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019971	protein coding gene	Chr11:124413466-124442617 (-)
PWK/PhJ	MGP_PWKPhJ_G0018610	protein coding gene	Chr11:120911583-120939030 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0018401	protein coding gene	Chr11:124170631-124199785 (-)
WSB/EiJ	MGP_WSBEiJ_G0018896	protein coding gene	Chr11:124389339-124418814 (-)

Human Ortholog

OGFOD3, 2-oxoglutarate and iron dependent oxygenase domain containing 3

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

OGFOD3, 2-oxoglutarate and iron dependent oxygenase domain containing 3
Synonyms

C17orf101
Links

HGNC:26174

NCBI Gene ID: 79701

neXtProt AC: NX_Q6PK18

UniProt: Q6PK18
Chr Location

17q25.3; chr17:82389210-82418637 (-) GRCh38

Alliance of Genome Resources

Ogfod3 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: OGFOD3
Gene Tree

Ogfod3

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
6 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Targeted

3
Incidental Mutations

APF
Find Mice (IMSR)

9 strains or lines available

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All GO Annotations

8
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development	DNA-templated transcription

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

717
Tissues

9
cDNA Data

32
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ogfod3

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Ogfod3 interacts with 42 markers (Mir15a, Mir15b, Mir16-1, ...) View All

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All Sequences

32
RefSeq

2
UniProt

1
CCDS

CCDS25770.1

Ensembl

ENSMUSG00000025169 (Evidence)
NCBI Gene

66179

			Length	Strain/Species	Flank
genomic	66179	NCBI Gene Model \| MGI Sequence Detail	27056	C57BL/6J	± kb
transcript	NM_025402	RefSeq \| MGI Sequence Detail	1243	C57BL/6
polypeptide	Q9D136	UniProt \| EBI \| MGI Sequence Detail	315	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000059870 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

(term hierarchy)
EC

1.14.11.-
InterPro Domains

IPR039210 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

IPR005123 Oxoglutarate/iron-dependent dioxygenase

IPR006620 Prolyl 4-hydroxylase, alpha subunit

IPR044862 Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain

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All nucleic 32

cDNA 32

Microarray probesets 3

Summaries

All 29

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

TSS for Ogfod3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr112451	Chr11:121095756-121095803 (-)	-306 bp
Tssr112450	Chr11:121095452-121095543 (-)	-24 bp
Tssr112449	Chr11:121087178-121087181 (-)	8,294 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/28/2023 MGI 6.22