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Ogfod3 Gene Detail
Summary
  • Symbol
    Ogfod3
  • Name
    2-oxoglutarate and iron-dependent oxygenase domain containing 3
  • Synonyms
    1110031I02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913429
    NCBI Gene: 66179
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:121068419-121095474 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 85.04 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    952 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913429
 protein coding gene Chr11:121068417-121095537 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019541
 protein coding gene Chr11:125715249-125743212 (-)
A/J MGP_AJ_G0019508
 protein coding gene Chr11:120101817-120124037 (-)
AKR/J MGP_AKRJ_G0019478
 protein coding gene Chr11:123736884-123763876 (-)
BALB/cJ MGP_BALBcJ_G0019483
 protein coding gene Chr11:120468050-120495493 (-)
C3H/HeJ MGP_C3HHeJ_G0019289
 protein coding gene Chr11:124060382-124089547 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019932
 protein coding gene Chr11:129528907-129555678 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017557
 protein coding gene Chr11:117080643-117110590 (-)
CAST/EiJ MGP_CASTEiJ_G0018843
 protein coding gene Chr11:125561923-125593952 (-)
CBA/J MGP_CBAJ_G0019260
 protein coding gene Chr11:134564444-134591182 (-)
DBA/2J MGP_DBA2J_G0019373
 protein coding gene Chr11:119466465-119494888 (-)
FVB/NJ MGP_FVBNJ_G0019364
 protein coding gene Chr11:119183258-119211007 (-)
LP/J MGP_LPJ_G0019444
 protein coding gene Chr11:125991952-126019536 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019397
 protein coding gene Chr11:133375238-133402793 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019971
 protein coding gene Chr11:124413466-124442617 (-)
PWK/PhJ MGP_PWKPhJ_G0018610
 protein coding gene Chr11:120911583-120939030 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018401
 protein coding gene Chr11:124170631-124199785 (-)
WSB/EiJ MGP_WSBEiJ_G0018896
 protein coding gene Chr11:124389339-124418814 (-)



Homology
more
  • Human Ortholog
    OGFOD3, 2-oxoglutarate and iron dependent oxygenase domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OGFOD3, 2-oxoglutarate and iron dependent oxygenase domain containing 3
  • Synonyms
    C17orf101
  • Links
    NCBI Gene ID: 79701
    UniProt: Q6PK18

  • Chr Location
    17q25.3; chr17:82389210-82418637 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    9
  • cDNA Data
    32
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66179 NCBI Gene Model | MGI Sequence Detail 27056 C57BL/6J ±  kb
transcript NM_025402 RefSeq | MGI Sequence Detail 1243 C57BL/6  
polypeptide Q9D136 UniProt | EBI | MGI Sequence Detail 315 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000059870 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3
    (term hierarchy)
  • EC
    1.14.11.-
  • InterPro Domains
    IPR039210 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3
    IPR005123 Oxoglutarate/iron-dependent dioxygenase
    IPR006620 Prolyl 4-hydroxylase, alpha subunit
    IPR044862 Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain
  • GlyGen
    Q9D136 2 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory