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Prxl2c Gene Detail
Summary
  • Symbol
    Prxl2c
  • Name
    peroxiredoxin like 2C
  • Synonyms
    1110018J18Rik, Aaed1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913379
    NCBI Gene: 66129
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:64437612-64460524 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 33.26 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    330 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913379
 protein coding gene Chr13:64423094-64460524 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020677
 protein coding gene Chr13:64315873-64336736 (-)
A/J MGP_AJ_G0020631
 protein coding gene Chr13:61983760-62003500 (-)
AKR/J MGP_AKRJ_G0020608
 protein coding gene Chr13:64034434-64055485 (-)
BALB/cJ MGP_BALBcJ_G0020629
 protein coding gene Chr13:62401993-62422710 (-)
C3H/HeJ MGP_C3HHeJ_G0020424
 protein coding gene Chr13:63558379-63580704 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021065
 protein coding gene Chr13:66379681-66403258 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018641
 protein coding gene Chr13:59634228-59654787 (-)
CAST/EiJ MGP_CASTEiJ_G0019941
 protein coding gene Chr13:63573984-63597842 (-)
CBA/J MGP_CBAJ_G0020384
 protein coding gene Chr13:68936659-68960449 (-)
DBA/2J MGP_DBA2J_G0020509
 protein coding gene Chr13:61813212-61832804 (-)
FVB/NJ MGP_FVBNJ_G0020488
 protein coding gene Chr13:60913634-60933044 (-)
LP/J MGP_LPJ_G0020583
 protein coding gene Chr13:64593292-64616376 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020517
 protein coding gene Chr13:67877394-67900289 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021107
 protein coding gene Chr13:63349100-63371708 (-)
PWK/PhJ MGP_PWKPhJ_G0019695
 protein coding gene Chr13:61376481-61396348 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019521
 protein coding gene Chr13:61511521-61530127 (-)
WSB/EiJ MGP_WSBEiJ_G0020001
 protein coding gene Chr13:63825252-63848637 (-)



Homology
more
  • Human Ortholog
    PRXL2C, peroxiredoxin like 2C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRXL2C, peroxiredoxin like 2C
  • Synonyms
    AAED1, C9orf21
  • Links
    NCBI Gene ID: 195827
    neXtProt AC: NX_Q7RTV5
    UniProt: Q7RTV5

  • Chr Location
    9q22.33; chr9:96639577-96655317 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    2
  • Genomic Mutations
    1 involving Prxl2c
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    49
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66129 NCBI Gene Model | MGI Sequence Detail 22913 C57BL/6J ±  kb
transcript NM_025370 RefSeq | MGI Sequence Detail 3010 C57BL/6  
polypeptide Q9D1A0 UniProt | EBI | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 49

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145300
References
more
  • Summaries
    All 31
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory