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Syncrip Gene Detail
Summary
  • Symbol
    Syncrip
  • Name
    synaptotagmin binding, cytoplasmic RNA interacting protein
  • Synonyms
    2610109K23Rik, 4632417O19Rik, GRY-RBP, hnRNP Q, Nsap1, Nsap1l, pp68, RRM RNA binding protein GRY-RBP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891690
    NCBI Gene: 56403
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:88331417-88364645 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 47.24 cM, cytoband E3.2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    499 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891690
 protein coding gene Chr9:88329062-88364645 (-)
129S1/SvImJ ENSMUSG00200005151
 protein coding gene Chr9:85432878-85466644 (-)
A/J ENSMUSG00195006793
 protein coding gene Chr9:85195543-85229314 (-)
AKR/J ENSMUSG00220019277
 protein coding gene Chr9:85349121-85382895 (-)
BALB/cJ ENSMUSG00180006459
 protein coding gene Chr9:85300376-85334145 (-)
C3H/HeJ ENSMUSG00175004497
 protein coding gene Chr9:85359927-85393694 (-)
C57BL/6NJ ENSMUSG00215007820
 protein coding gene Chr9:85336589-85370351 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032508
 protein coding gene Chr9:84929264-84935085 (-)
CAST/EiJ ENSTCUG00005003944
 protein coding gene Chr9:84853296-84887169 (-)
CBA/J ENSMUSG00210005537
 protein coding gene Chr9:85458771-85492543 (-)
DBA/2J ENSMUSG00185001227
 protein coding gene Chr9:85402978-85436755 (-)
FVB/NJ ENSMUSG00205003953
 protein coding gene Chr9:85595260-85629014 (-)
JF1/MsJ ENSUMUG00000026597
 protein coding gene Chr9:85296692-85330847 (-)
LP/J ENSMUSG00230007692
 protein coding gene Chr9:85561126-85594892 (-)
NOD/ShiLtJ ENSMUSG00190010674
 protein coding gene Chr9:85528082-85561850 (-)
NZO/HlLtJ ENSMUSG00225015873
 protein coding gene Chr9:85703915-85737691 (-)
PWK/PhJ ENSLUMG00010002793
 protein coding gene Chr9:85201393-85235385 (-)
SPRET/EiJ ENSMSPG00010002319
 protein coding gene Chr9:86733391-86769009 (-)
WSB/EiJ ENSIUOG00005003530
 protein coding gene Chr9:84869898-84903650 (-)



Homology
more
  • Human Ortholog
    SYNCRIP, synaptotagmin binding cytoplasmic RNA interacting protein
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYNCRIP, synaptotagmin binding cytoplasmic RNA interacting protein
  • Synonyms
    GRY-RBP, GRYRBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1, PP68
  • Links
    NCBI Gene ID: 10492
    UniProt: O60506

  • Chr Location
    6q14.3; chr6:85607779-85644063 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    43
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    821
  • Tissues
    147
  • cDNA Data
    27
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56403 NCBI Gene Model | MGI Sequence Detail 33229 C57BL/6J ±  kb
    transcript NM_019796 RefSeq | MGI Sequence Detail 6933 C57BL/6  
    polypeptide Q7TMK9 UniProt | EBI | MGI Sequence Detail 623 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      11 Sequences
    • Protein Ontology
      PR:000015874 heterogeneous nuclear ribonucleoprotein Q
      (term hierarchy)
    • InterPro Domains
      IPR041337 Heterogeneous nuclear ribonucleoprotein Q acidic domain
      IPR034544 Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1
      IPR034548 Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2
      IPR006535 HnRNP R/Q splicing factor
      IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
      IPR035979 RNA-binding domain superfamily
      IPR000504 RNA recognition motif domain
    • GlyGen
      Q7TMK9 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 31
      cDNA 27
      Primer pair 3
      Other 1
      Antibodies 3

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGI:1914396, MGI:1925510, MGI:1930916
    References
    more
    • Summaries
      All 74
      Developmental Gene Expression 7
      Gene Ontology 12
      Phenotypes 18
    • Earliest
      J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
    • Latest
      J:361907 Wu J, et al., Posttranscriptional Control of Neural Progenitors Temporal Dynamics During Neocortical Development by Syncrip. Adv Sci (Weinh). 2025 Feb;12(8):e2411732
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory