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Psg27 Gene Detail
Summary
  • Symbol
    Psg27
  • Name
    pregnancy-specific beta-1-glycoprotein 27
  • Synonyms
    cea15, EG545925
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891359
    NCBI Gene: 545925
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:18290439-18301230 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.15 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    582 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891359
protein coding gene Chr7:18290439-18301230 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0031715
protein coding gene Chr7:16139986-16150176 (-)
AKR/J MGP_AKRJ_G0031640
protein coding gene Chr7:16530432-16540433 (-)
BALB/cJ MGP_BALBcJ_G0031721
protein coding gene Chr7:16359757-16371071 (-)
C3H/HeJ MGP_C3HHeJ_G0031444
protein coding gene Chr7:16780096-16790453 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032186
protein coding gene Chr7:17301610-17326275 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031405
protein coding gene Chr7:17898306-17909129 (-)
DBA/2J MGP_DBA2J_G0031560
protein coding gene Chr7:15991254-16001270 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0031644
protein coding gene Chr7:16720557-16728461 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031548
protein coding gene Chr7:17770163-17783015 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032216
protein coding gene Chr7:16210186-16227777 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CEACAM4, CEA cell adhesion molecule 4
  • Vertebrate Orthologs
    23
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEACAM4, CEA cell adhesion molecule 4
  • Synonyms
    CGM7, CGM7_HUMAN, NCA
  • Links
    NCBI Gene ID: 1089
    neXtProt AC: NX_O75871
    UniProt: O75871

  • Chr Location
    19q13.2; chr19:41613436-41627074 (-)  GRCh38

  • Human Ortholog
    CEACAM7, CEA cell adhesion molecule 7
  • Synonyms
    CGM2
  • Links
    NCBI Gene ID: 1087
    neXtProt AC: NX_Q14002
    UniProt: Q14002

  • Chr Location
    19q13.2; chr19:41673303-41706976 (-)  GRCh38

  • Human Ortholog
    PSG5, pregnancy specific beta-1-glycoprotein 5
  • Synonyms
    FL-NCA-3, PSG
  • Links
    NCBI Gene ID: 5673
    neXtProt AC: NX_Q15238
    UniProt: Q15238

  • Chr Location
    19q13.31; chr19:43166256-43186536 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 545925 NCBI Gene Model | MGI Sequence Detail 10792 C57BL/6J ±  kb
    transcript NM_001037168 RefSeq | MGI Sequence Detail 1989 Not Specified  
    polypeptide NP_001032245 RefSeq | MGI Sequence Detail 474 Not Specified  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR007110 Immunoglobulin-like domain
      IPR036179 Immunoglobulin-like domain superfamily
      IPR013783 Immunoglobulin-like fold
      IPR003599 Immunoglobulin subtype
      IPR003598 Immunoglobulin subtype 2
      IPR013106 Immunoglobulin V-set domain
    • GlyGen
      Q497W2 2 sites, 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 38
      cDNA 38

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:3649013
    References
    more
    • Summaries
      All 19
      Gene Ontology 2
      Phenotypes 4
    • Earliest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    07/05/2024
    MGI 6.24
    The Jackson Laboratory