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Atp6v0b Gene Detail
Summary
  • Symbol
    Atp6v0b
  • Name
    ATPase, H+ transporting, lysosomal V0 subunit B
  • Synonyms
    2310024H13Rik, Atp6f, VMA16
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890510
    NCBI Gene: 114143
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:117741523-117744530 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.73 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    111 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890510
protein coding gene Chr4:117741523-117744548 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028658
protein coding gene Chr4:118888732-118891740 (-)
A/J MGP_AJ_G0028619
protein coding gene Chr4:114301629-114304640 (-)
AKR/J MGP_AKRJ_G0028569
protein coding gene Chr4:116808471-116811453 (-)
BALB/cJ MGP_BALBcJ_G0028640
protein coding gene Chr4:114940371-114943378 (-)
C3H/HeJ MGP_C3HHeJ_G0028354
protein coding gene Chr4:118383461-118386468 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029081
protein coding gene Chr4:123466979-123469992 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026365
protein coding gene Chr4:108330543-108333488 (-)
CAST/EiJ MGP_CASTEiJ_G0027788
protein coding gene Chr4:115610107-115613095 (-)
CBA/J MGP_CBAJ_G0028321
protein coding gene Chr4:126834956-126837963 (-)
DBA/2J MGP_DBA2J_G0028469
protein coding gene Chr4:114919438-114922446 (-)
FVB/NJ MGP_FVBNJ_G0028437
protein coding gene Chr4:113434917-113437924 (-)
LP/J MGP_LPJ_G0028571
protein coding gene Chr4:119075714-119078722 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028464
protein coding gene Chr4:131756053-131759041 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029118
protein coding gene Chr4:117950540-117953550 (-)
PWK/PhJ MGP_PWKPhJ_G0027514
protein coding gene Chr4:111740053-111743067 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027337
protein coding gene Chr4:114267193-114270197 (-)
WSB/EiJ MGP_WSBEiJ_G0027867
protein coding gene Chr4:117834285-117837295 (-)



Homology
more
  • Human Ortholog
    ATP6V0B, ATPase H+ transporting V0 subunit b
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP6V0B, ATPase H+ transporting V0 subunit b
  • Synonyms
    ATP6F, HATPL, VMA16
  • Links
    NCBI Gene ID: 533
    neXtProt AC: NX_Q99437
    UniProt: Q99437

  • Chr Location
    1p34.1; chr1:43974487-43978295 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033379 Ensembl Gene Model | MGI Sequence Detail 3008 C57BL/6J ±  kb
    transcript ENSMUST00000036380 Ensembl | MGI Sequence Detail 1000 Not Applicable  
    polypeptide ENSMUSP00000047682 Ensembl | MGI Sequence Detail 205 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 122
      Genomic 1
      cDNA 120
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1913620
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    09/24/2024
    MGI 6.24
    The Jackson Laboratory