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Pdss1 Gene Detail
Summary
  • Symbol
    Pdss1
  • Name
    prenyl (solanesyl) diphosphate synthase, subunit 1
  • Synonyms
    2610203G20Rik, 2700031G06Rik, mSPS1, Tprt
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889278
    NCBI Gene: 56075
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:22785534-22830278 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 15.17 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    901 from dbSNP Build 142
  • Strain Annotations
    28
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889278
 protein coding gene Chr2:22784393-22830278 (+)
129S1/SvImJ ENSMUSGG00200054426
 protein coding gene Chr2:19767815-19774726 (+)
129S1/SvImJ ENSMUSG00200041919
 protein coding gene Chr2:19763514-19767879 (+)
A/J ENSMUSGG00195055280
 protein coding gene Chr2:19863077-19869982 (+)
A/J ENSMUSG00195018753
 protein coding gene Chr2:19858772-19863141 (+)
AKR/J ENSMUSGG00220054408
 protein coding gene Chr2:19984208-19991113 (+)
AKR/J ENSMUSG00220013196
 protein coding gene Chr2:19979903-19984272 (+)
BALB/cJ ENSMUSGG00180055282
 protein coding gene Chr2:19868957-19875862 (+)
BALB/cJ ENSMUSG00180036659
 protein coding gene Chr2:19864656-19869021 (+)
C3H/HeJ ENSMUSG00175020724
 protein coding gene Chr2:19829281-19833645 (+)
C3H/HeJ ENSMUSGG00175054953
 protein coding gene Chr2:19833581-19840484 (+)
C57BL/6NJ ENSMUSG00215026981
 protein coding gene Chr2:19889042-19893407 (+)
C57BL/6NJ ENSMUSGG00215055593
 protein coding gene Chr2:19893343-19900248 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023224
 protein coding gene Chr2:18878400-18926653 (+)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054871
 protein coding gene Chr2:19872557-19879462 (+)
CBA/J ENSMUSG00210003352
 protein coding gene Chr2:19868257-19872621 (+)
DBA/2J ENSMUSGG00185057757
 protein coding gene Chr2:19777428-19784333 (+)
DBA/2J ENSMUSG00185037710
 protein coding gene Chr2:19773123-19777492 (+)
FVB/NJ ENSMUSGG00205054442
 protein coding gene Chr2:19797877-19804791 (+)
FVB/NJ ENSMUSG00205013469
 protein coding gene Chr2:19793573-19797941 (+)
JF1/MsJ ENSUMUG00000003562
 protein coding gene Chr2:19661263-19707386 (+)
LP/J ENSMUSGG00230055302
 protein coding gene Chr2:21703809-21710720 (+)
LP/J ENSMUSG00230035377
 protein coding gene Chr2:21699509-21703873 (+)
NOD/ShiLtJ ENSMUSGG00190054841
 protein coding gene Chr2:19863547-19870452 (+)
NOD/ShiLtJ ENSMUSG00190013332
 protein coding gene Chr2:19859246-19863611 (+)
NZO/HlLtJ ENSMUSGG00225055491
 protein coding gene Chr2:29454419-29461326 (+)
NZO/HlLtJ ENSMUSG00225001226
 protein coding gene Chr2:29450115-29454483 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010043738
 protein coding gene Chr2:20351375-20397190 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PDSS1, decaprenyl diphosphate synthase subunit 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PDSS1, decaprenyl diphosphate synthase subunit 1
  • Synonyms
    COQ1, COQ10D2, COQ1A, DPS, hDPS1, SPS, TPRT, TPT, TPT 1
  • Links
    NCBI Gene ID: 23590
    UniProt: Q5T2R2

  • Chr Location
    10p12.1; chr10:26697669-26746798 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PDSS1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    697
  • Tissues
    96
  • cDNA Data
    5
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026784 Ensembl Gene Model | MGI Sequence Detail 44745 C57BL/6J ±  kb
    transcript ENSMUST00000053729 Ensembl | MGI Sequence Detail 1642 Not Applicable  
    polypeptide ENSMUSP00000055689 Ensembl | MGI Sequence Detail 409 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 8
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1914443, MGI:1919716
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 2
      Gene Ontology 14
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory