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Zfp276 Gene Detail
Summary
  • Symbol
    Zfp276
  • Name
    zinc finger protein (C2H2 type) 276
  • Synonyms
    D8Ertd370e, D8Ertd377e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1888495
    NCBI Gene: 57247
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:123980934-123996484 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 72.09 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    451 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1888495
 protein coding gene Chr8:123980934-123997290 (+)
129S1/SvImJ ENSMUSG00200042821
 protein coding gene Chr8:118310904-118326447 (+)
A/J ENSMUSG00195026260
 protein coding gene Chr8:118603632-118618920 (+)
AKR/J ENSMUSG00220038328
 protein coding gene Chr8:118793171-118808660 (+)
BALB/cJ ENSMUSG00180023564
 protein coding gene Chr8:118649616-118664903 (+)
C3H/HeJ ENSMUSG00175030057
 protein coding gene Chr8:118705077-118720565 (+)
C57BL/6NJ ENSMUSG00215025090
 protein coding gene Chr8:118287235-118302787 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031685
 protein coding gene Chr8:114420621-114435926 (+)
CAST/EiJ ENSTCUG00005031395
 protein coding gene Chr8:118023850-118039375 (+)
CBA/J ENSMUSG00210032368
 protein coding gene Chr8:118639673-118655225 (+)
DBA/2J ENSMUSG00185033650
 protein coding gene Chr8:124744611-124760158 (+)
FVB/NJ ENSMUSG00205026240
 protein coding gene Chr8:117605906-117621457 (+)
JF1/MsJ ENSUMUG00000020156
 protein coding gene Chr8:127043291-127058580 (+)
LP/J ENSMUSG00230028513
 protein coding gene Chr8:128362307-128377850 (+)
NOD/ShiLtJ ENSMUSG00190018183
 protein coding gene Chr8:118740150-118755701 (+)
NZO/HlLtJ ENSMUSG00225041733
 protein coding gene Chr8:131745081-131760631 (+)
PWK/PhJ ENSLUMG00010032074
 protein coding gene Chr8:118447622-118462919 (+)
SPRET/EiJ ENSMSPG00010036600
 protein coding gene Chr8:120636544-120651612 (+)
WSB/EiJ ENSIUOG00005027563
 protein coding gene Chr8:119425185-119440732 (+)



Homology
more
  • Human Ortholog
    ZNF276, zinc finger protein 276
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF276, zinc finger protein 276
  • Synonyms
    CENP-Z, CENPZ, ZADT, ZFP276, ZNF477
  • Links
    NCBI Gene ID: 92822
    UniProt: Q8N554

  • Chr Location
    16q24.3; chr16:89720368-89740925 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    683
  • Tissues
    73
  • cDNA Data
    17
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000001065 Ensembl Gene Model | MGI Sequence Detail 15551 C57BL/6J ±  kb
    transcript ENSMUST00000001092 Ensembl | MGI Sequence Detail 4071 Not Applicable  
    polypeptide ENSMUSP00000001092 Ensembl | MGI Sequence Detail 614 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 24
      Genomic 1
      cDNA 19
      Primer pair 4

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1196248, MGI:1196409, MGI:2142748
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 5
      Gene Ontology 7
      Phenotypes 5
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:324574 Aberle T, et al., Transcription factor Zfp276 drives oligodendroglial differentiation and myelination by switching off the progenitor cell program. Nucleic Acids Res. 2022 Feb 28;50(4):1951-1968
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory