About   Help   FAQ
Gabarap Gene Detail
Summary
  • Symbol
    Gabarap
  • Name
    gamma-aminobutyric acid receptor associated protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861742
    NCBI Gene: 56486
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr11:69882196-69885775 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.95 cM, cytoband B4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1861742
 protein coding gene Chr11:69881969-69885777 (+)
129S1/SvImJ ENSMUSG00200049426
 protein coding gene Chr11:66828959-66832765 (+)
A/J ENSMUSG00195040942
 protein coding gene Chr11:66855428-66859237 (+)
AKR/J ENSMUSG00220054082
 protein coding gene Chr11:66964427-66968238 (+)
BALB/cJ ENSMUSG00180036225
 protein coding gene Chr11:66923978-66927793 (+)
C3H/HeJ ENSMUSG00175053827
 protein coding gene Chr11:66874170-66877983 (+)
C57BL/6NJ ENSMUSG00215052077
 protein coding gene Chr11:66651337-66655148 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016611
 protein coding gene Chr11:64740485-64744004 (+)
CAST/EiJ ENSTCUG00005053258
 protein coding gene Chr11:66416912-66420736 (+)
CBA/J ENSMUSG00210054284
 protein coding gene Chr11:66728247-66732057 (+)
DBA/2J ENSMUSG00185041625
 protein coding gene Chr11:66930293-66934076 (+)
FVB/NJ ENSMUSG00205053139
 protein coding gene Chr11:66822022-66825784 (+)
JF1/MsJ ENSUMUG00000050989
 protein coding gene Chr11:67328723-67332502 (+)
LP/J ENSMUSG00230053664
 protein coding gene Chr11:68039299-68043102 (+)
NOD/ShiLtJ ENSMUSG00190053919
 protein coding gene Chr11:66958184-66961990 (+)
NZO/HlLtJ ENSMUSG00225044020
 protein coding gene Chr11:70220745-70224546 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010045752
 protein coding gene Chr11:67574112-67577838 (+)
WSB/EiJ ENSIUOG00005047604
 protein coding gene Chr11:66859598-66863395 (+)



Homology
more
  • Human Ortholog
    GABARAP, GABA type A receptor-associated protein
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GABARAP, GABA type A receptor-associated protein
  • Synonyms
    ATG8A, GABARAP-a, MM46
  • Links
    NCBI Gene ID: 11337
    UniProt: O95166

  • Chr Location
    17p13.1; chr17:7240008-7242449 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    20 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    5
  • Targeted
    5
  • Genomic Mutations
    2 involving Gabarap
  • Find Mice (IMSR)
    21 strains or lines available
Mice homozygous for a disruption in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    79
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    602
  • Tissues
    2
  • cDNA Data
    242
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56486 NCBI Gene Model | MGI Sequence Detail 3580 C57BL/6J ±  kb
transcript NM_019749 RefSeq | MGI Sequence Detail 1122 ZRU/MplStud  
polypeptide Q9DCD6 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 242
    cDNA 242
    Antibodies 1

    Microarray probesets 3
References
more
  • Summaries
    All 82
    Developmental Gene Expression 2
    Gene Ontology 15
    Phenotypes 20
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:373425 Makareeva E, et al., LC3 and GABARAP independent autophagy of misfolded procollagen in mouse osteoblasts. Autophagy. 2025 Sep 9;:1-16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory