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Pcdh7 Gene Detail
Summary
  • Symbol
    Pcdh7
  • Name
    protocadherin 7
  • Synonyms
    BH-protocadherin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860487
    NCBI Gene: 54216
  • Alliance
    gene page
  • Transcription Start Sites
    59 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:57875309-58290572 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 31.65 cM, cytoband C3-D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2567 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860487
 protein coding gene Chr5:57873487-58290578 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029558
 protein coding gene Chr5:57009291-57447580 (+)
A/J MGP_AJ_G0029526
 protein coding gene Chr5:54902628-55317546 (+)
AKR/J MGP_AKRJ_G0029474
 protein coding gene Chr5:56694261-57113062 (+)
BALB/cJ MGP_BALBcJ_G0029535
 protein coding gene Chr5:55506216-55928366 (+)
C3H/HeJ MGP_C3HHeJ_G0029258
 protein coding gene Chr5:56979986-57416930 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029989
 protein coding gene Chr5:59295663-59771275 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027229
 protein coding gene Chr5:51704053-52111603 (+)
CAST/EiJ MGP_CASTEiJ_G0028666
 protein coding gene Chr5:55981501-56425407 (+)
CBA/J MGP_CBAJ_G0029227
 protein coding gene Chr5:61265943-61751352 (+)
DBA/2J MGP_DBA2J_G0029373
 protein coding gene Chr5:54961307-55390231 (+)
FVB/NJ MGP_FVBNJ_G0029333
 protein coding gene Chr5:54223080-54655206 (+)
LP/J MGP_LPJ_G0029458
 protein coding gene Chr5:57390407-57833670 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029361
 protein coding gene Chr5:63003707-63580902 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030022
 protein coding gene Chr5:56297764-56732650 (+)
PWK/PhJ MGP_PWKPhJ_G0028390
 protein coding gene Chr5:54004609-54424009 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028224
 protein coding gene Chr5:55748516-56171672 (+)
WSB/EiJ MGP_WSBEiJ_G0028747
 protein coding gene Chr5:56455670-56881594 (+)



Homology
more
  • Human Ortholog
    PCDH7, protocadherin 7
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDH7, protocadherin 7
  • Synonyms
    BH-Pcdh, BHPCDH, PPP1R120
  • Links
    NCBI Gene ID: 5099
    neXtProt AC: NX_O60245
    UniProt: O60245

  • Chr Location
    4p15.1; chr4:30720369-31146805 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased trabecular bone mass, volume, and thickness, decreased trabecular spacing, and reduced osteoclast numbers.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1006
  • Tissues
    55
  • cDNA Data
    13
  • Literature Summary
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029108 Ensembl Gene Model | MGI Sequence Detail 415264 C57BL/6J ±  kb
    transcript ENSMUST00000191837 Ensembl | MGI Sequence Detail 8785 Not Applicable  
    polypeptide ENSMUSP00000142319 Ensembl | MGI Sequence Detail 1255 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 13
      Primer pair 5
      Other 1

      Microarray probesets 6
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 14
      Gene Ontology 3
      Phenotypes 21
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory