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Ammecr1 Gene Detail
Summary
  • Symbol
    Ammecr1
  • Name
    AMMECR nuclear protein 1
  • Synonyms
    6230420G18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860206
    NCBI Gene: 56068
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:141634142-141749722 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 63.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    598 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860206
 protein coding gene ChrX:141634142-141749724 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036152
 protein coding gene ChrX:140382148-140496298 (-)
A/J MGP_AJ_G0036129
 protein coding gene ChrX:139768446-139874872 (-)
AKR/J MGP_AKRJ_G0036055
 protein coding gene ChrX:144241939-144359641 (-)
BALB/cJ MGP_BALBcJ_G0036120
 protein coding gene ChrX:137986937-138102662 (-)
C3H/HeJ MGP_C3HHeJ_G0035828
 protein coding gene ChrX:140478972-140593086 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036643
 protein coding gene ChrX:144387474-144496080 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033467
 protein coding gene ChrX:131305583-131413682 (-)
CAST/EiJ MGP_CASTEiJ_G0035119
 protein coding gene ChrX:121187277-121297067 (-)
CBA/J MGP_CBAJ_G0035805
 protein coding gene ChrX:148912309-149041382 (-)
DBA/2J MGP_DBA2J_G0035963
 protein coding gene ChrX:138826187-138937886 (-)
FVB/NJ MGP_FVBNJ_G0035897
 protein coding gene ChrX:138051206-138165161 (-)
LP/J MGP_LPJ_G0036054
 protein coding gene ChrX:141341990-141451136 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035933
 protein coding gene ChrX:156550397-156670990 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036680
 protein coding gene ChrX:139691099-139799823 (-)
PWK/PhJ MGP_PWKPhJ_G0034813
 protein coding gene ChrX:117994007-118102261 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034638
 protein coding gene ChrX:121718394-121832796 (-)
WSB/EiJ MGP_WSBEiJ_G0035254
 protein coding gene ChrX:138060949-138168850 (-)



Homology
more
  • Human Ortholog
    AMMECR1, AMMECR nuclear protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AMMECR1, AMMECR nuclear protein 1
  • Synonyms
    AMMERC1, MFHIEN
  • Links
    NCBI Gene ID: 9949
    neXtProt AC: NX_Q9Y4X0
    UniProt: Q9Y4X0

  • Chr Location
    Xq23; chrX:110194186-110440233 (-)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with human AMMECR1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 images
    8 phenotype references
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    712
  • Tissues
    6
  • cDNA Data
    24
  • Literature Summary
    1
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56068 NCBI Gene Model | MGI Sequence Detail 115581 C57BL/6J ±  kb
transcript NM_019496 RefSeq | MGI Sequence Detail 5435 C57BL/6  
polypeptide Q9JHT5 UniProt | EBI | MGI Sequence Detail 344 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    Genomic 1
    cDNA 25

    Microarray probesets 2
Other
Accession IDs
less
MGI:1923390
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:62787 Vitelli F, et al., Identification and characterization of mouse orthologs of the AMMECR1 and FACL4 genes deleted in AMME syndrome: orthology of Xq22.3 and MmuXF1-F3. Cytogenet Cell Genet. 2000;88(3-4):259-63
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/21/2023
MGI 6.22 		The Jackson Laboratory