About   Help   FAQ
Plpp2 Gene Detail
Summary
  • Symbol
    Plpp2
  • Name
    phospholipid phosphatase 2
  • Synonyms
    Lpp2, Ppap2c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354945
    NCBI Gene: 50784
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79362258-79369621 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    248 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354945
 protein coding gene Chr10:79362258-79369630 (-)
129S1/SvImJ ENSMUSG00200049340
 protein coding gene Chr10:75985355-75992894 (-)
A/J ENSMUSG00195037123
 protein coding gene Chr10:76380842-76388379 (-)
AKR/J ENSMUSG00220044628
 protein coding gene Chr10:75978412-75985951 (-)
BALB/cJ ENSMUSG00180051564
 protein coding gene Chr10:76391379-76398918 (-)
C3H/HeJ ENSMUSG00175043639
 protein coding gene Chr10:76262035-76269574 (-)
C57BL/6NJ ENSMUSG00215051884
 protein coding gene Chr10:76003727-76011266 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015526
 protein coding gene Chr10:73502797-73510479 (-)
CAST/EiJ ENSTCUG00005046332
 protein coding gene Chr10:75888810-75896323 (-)
CBA/J ENSMUSG00210047637
 protein coding gene Chr10:76118125-76125664 (-)
DBA/2J ENSMUSG00185047191
 protein coding gene Chr10:76460509-76468048 (-)
FVB/NJ ENSMUSG00205047330
 protein coding gene Chr10:76173275-76180814 (-)
JF1/MsJ ENSUMUG00000050412
 protein coding gene Chr10:77691849-77699368 (-)
LP/J ENSMUSG00230044906
 protein coding gene Chr10:78230287-78237826 (-)
NOD/ShiLtJ ENSMUSG00190033016
 protein coding gene Chr10:76374345-76381884 (-)
NZO/HlLtJ ENSMUSG00225050473
 protein coding gene Chr10:82516757-82524296 (-)
PWK/PhJ ENSLUMG00010050289
 protein coding gene Chr10:76050945-76058458 (-)
SPRET/EiJ ENSMSPG00010046413
 protein coding gene Chr10:77672796-77680256 (-)
WSB/EiJ ENSIUOG00005049603
 protein coding gene Chr10:76077845-76085393 (-)



Homology
more
  • Human Ortholog
    PLPP2, phospholipid phosphatase 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLPP2, phospholipid phosphatase 2
  • Synonyms
    LPP2, PAP-2c, PAP2-g, PPAP2C
  • Links
    NCBI Gene ID: 8612
    UniProt: O43688

  • Chr Location
    19p13.3; chr19:278504-291403 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    57
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    741
  • Tissues
    109
  • cDNA Data
    144
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 50784 NCBI Gene Model | MGI Sequence Detail 7364 C57BL/6J ±  kb
transcript NM_015817 RefSeq | MGI Sequence Detail 1651 ZRU/MplStud  
polypeptide Q9DAX2 UniProt | EBI | MGI Sequence Detail 276 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 148
    Genomic 1
    cDNA 146
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 44
    Developmental Gene Expression 5
    Gene Ontology 11
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory