Fbxo16 Gene Detail

Summary

• Symbol
  Fbxo16
• Name
  F-box protein 16
• Synonyms
  Fbx16

• Feature Type
  protein coding gene
• IDs
  MGI:1354706
  NCBI Gene: 50759
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr14:65504067-65561422 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 34.19 cM, cytoband D1
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  226 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1354706	protein coding gene	Chr14:65504067-65561422 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0021478	protein coding gene	Chr14:59867068-59917860 (+)
A/J	MGP_AJ_G0021437	protein coding gene	Chr14:58486513-58535777 (+)
AKR/J	MGP_AKRJ_G0021413	protein coding gene	Chr14:60518941-60568335 (+)
BALB/cJ	MGP_BALBcJ_G0021443	protein coding gene	Chr14:58422561-58470762 (+)
C3H/HeJ	MGP_C3HHeJ_G0021220	protein coding gene	Chr14:60164056-60212074 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021882	protein coding gene	Chr14:62643510-62692768 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019422	protein coding gene	Chr14:56413650-56464448 (+)
CAST/EiJ	MGP_CASTEiJ_G0020737	protein coding gene	Chr14:56643394-56696866 (+)
CBA/J	MGP_CBAJ_G0021187	protein coding gene	Chr14:64540424-64588189 (+)
DBA/2J	MGP_DBA2J_G0021310	protein coding gene	Chr14:58135942-58184610 (+)
FVB/NJ	MGP_FVBNJ_G0021289	protein coding gene	Chr14:57536471-57584220 (+)
LP/J	MGP_LPJ_G0021385	protein coding gene	Chr14:60903261-60957329 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021318	protein coding gene	Chr14:63646747-63700420 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021905	protein coding gene	Chr14:59698779-59750073 (+)
PWK/PhJ	MGP_PWKPhJ_G0020481	protein coding gene	Chr14:54841250-54893191 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020314	protein coding gene	Chr14:55652209-55699915 (+)
WSB/EiJ	MGP_WSBEiJ_G0020790	protein coding gene	Chr14:60004312-60056474 (+)

Homology

• Human Ortholog
  FBXO16, F-box protein 16

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  FBXO16, F-box protein 16
  
• Synonyms
  FBX16
• Links
  HGNC:13618

  NCBI Gene ID: 157574

  neXtProt AC: NX_Q8IX29

  UniProt: Q8IX29

  
  
• Chr Location
  8p21.1; chr8:28428408-28490318 (-)  GRCh38.p7

---

• Alliance of Genome Resources
  Fbxo16 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: FBXO16
• Gene Tree
  Fbxo16
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotype references
  

• All Mutations and Alleles
  10
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Gene trapped
  3
• Targeted
  5
• Genomic Mutations
  1 involving Fbxo16
• Incidental Mutations
  Mutagenetix
• Find Mice (IMSR)
  16 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  14

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase fbxo16
  ZFIN fbxo16

Interactions

• Fbxo16 interacts with 16 markers (Mir22, Mir103-1, Mir103-2, ...) View All

Sequences &
Gene Models

• All Sequences
  44
• RefSeq
  6
• UniProt
  4
• CCDS
  CCDS36956.1, CCDS88689.1

• Ensembl
  ENSMUSG00000034532 (Evidence)
• NCBI Gene
  50759

Representative Sequences			Length	Strain/Species
genomic	50759	NCBI Gene Model | MGI Sequence Detail	57356	C57BL/6J
transcript	NM_001360383	RefSeq | MGI Sequence Detail	3835	C57BL/6
polypeptide	Q9QZM9	UniProt | EBI | MGI Sequence Detail	334	Not Applicable

Protein
Information

• UniProt
  4 Sequences
• Protein Ontology
  PR:000007390 F-box only protein 16
  (term hierarchy)
• InterPro Domains
  IPR001810 F-box domain
  IPR036047 F-box-like domain superfamily

Molecular
Reagents

• All nucleic 14

  cDNA 14

  
  

  Microarray probesets 2

Other
Accession IDs

MGI:2444102

References

• Summaries
  All 29

  Phenotypes 9
• Earliest
  J:58149 Winston JT, et al., A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2
• Latest
  J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

TSS for Fbxo16:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr126206	Chr14:65504129-65504141 (+)	68 bp
Tssr126207	Chr14:65504153-65504201 (+)	110 bp