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Fbxl17 Gene Detail
Summary
  • Symbol
    Fbxl17
  • Name
    F-box and leucine-rich repeat protein 17
  • Synonyms
    6330576B01Rik, C130023C01Rik, Fbx13, Fbxo13
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354704
    NCBI Gene: 50758
  • Alliance
    gene page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:63364447-63807012 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 32.68 cM, cytoband E1.2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10703 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354704
 protein coding gene Chr17:63352944-63811179 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023970
 protein coding gene Chr17:65103076-65553367 (-)
A/J MGP_AJ_G0023928
 protein coding gene Chr17:63176913-63616338 (-)
AKR/J MGP_AKRJ_G0023897
 protein coding gene Chr17:64015768-64457819 (-)
BALB/cJ MGP_BALBcJ_G0023929
 protein coding gene Chr17:63093867-63529318 (-)
C3H/HeJ MGP_C3HHeJ_G0023693
 protein coding gene Chr17:64895633-65339464 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024375
 protein coding gene Chr17:67626582-68093526 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021821
 protein coding gene Chr17:59342088-59775905 (-)
CAST/EiJ MGP_CASTEiJ_G0023175
 protein coding gene Chr17:65241507-65697132 (-)
CBA/J MGP_CBAJ_G0023669
 protein coding gene Chr17:70318351-70786564 (-)
DBA/2J MGP_DBA2J_G0023797
 protein coding gene Chr17:61941764-62388825 (-)
FVB/NJ MGP_FVBNJ_G0023763
 protein coding gene Chr17:61427260-61873232 (-)
LP/J MGP_LPJ_G0023879
 protein coding gene Chr17:65849329-66297435 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023791
 protein coding gene Chr17:70452797-70940871 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024419
 protein coding gene Chr17:64501917-64953497 (-)
PWK/PhJ MGP_PWKPhJ_G0022921
 protein coding gene Chr17:61210028-61644182 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022732
 protein coding gene Chr17:61188664-61649177 (-)
WSB/EiJ MGP_WSBEiJ_G0023241
 protein coding gene Chr17:65140311-65587663 (-)



Homology
more
  • Human Ortholog
    FBXL17, F-box and leucine rich repeat protein 17
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXL17, F-box and leucine rich repeat protein 17
  • Synonyms
    Fbl17, Fbx13, FBXO13
  • Links
    NCBI Gene ID: 64839
    UniProt: Q9UF56

  • Chr Location
    5q21.3; chr5:107859035-108382098 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    3
  • cDNA Data
    55
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023965 Ensembl Gene Model | MGI Sequence Detail 442566 C57BL/6J ±  kb
transcript ENSMUST00000024761 Ensembl | MGI Sequence Detail 4925 Not Applicable  
polypeptide ENSMUSP00000024761 Ensembl | MGI Sequence Detail 701 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 55

    Microarray probesets 5
Other
Accession IDs
less
MGI:1923430, MGI:2146868, MGI:2147104, MGI:2443894
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:58149 Winston JT, et al., A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2
  • Latest
    J:234100 Raducu M, et al., SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development. EMBO J. 2016 Jul 1;35(13):1400-16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/09/2025
MGI 6.24 		The Jackson Laboratory