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Fbxw14 Gene Detail
Summary
  • Symbol
    Fbxw14
  • Name
    F-box and WD-40 domain protein 14
  • Synonyms
    E330009N23Rik, Fbx12, Fbxo12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354703
    NCBI Gene: 50757
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr9:109099858-109116744 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    18 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354703
 protein coding gene Chr9:109099857-109116797 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035331
 protein coding gene Chr9:111451863-111501067 (-)
A/J MGP_AJ_G0035310
 protein coding gene Chr9:107189550-107785847 (-)
AKR/J MGP_AKRJ_G0035242
 protein coding gene Chr9:109952498-110156695 (-)
BALB/cJ MGP_BALBcJ_G0035305
 protein coding gene Chr9:106849969-107487997 (-)
C3H/HeJ MGP_C3HHeJ_G0035014
 protein coding gene Chr9:110297182-110611337 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035824
 protein coding gene Chr9:114362437-114484408 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0034325
 protein coding gene Chr9:110438996-110541813 (-)
CBA/J MGP_CBAJ_G0034982
 protein coding gene Chr9:118592995-118593678 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0035090
 protein coding gene Chr9:105404540-105766384 (-)
LP/J MGP_LPJ_G0035219
 protein coding gene Chr9:111450687-112021071 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035129
 protein coding gene Chr9:119909547-119917331 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035847
 protein coding gene Chr9:110333653-110757787 (-)
PWK/PhJ MGP_PWKPhJ_G0034032
 protein coding gene Chr9:107215002-107330094 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0034445
 protein coding gene Chr9:110049696-110462658 (-)



Homology
more
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Synonyms
    FBW12, FBXO12, FBXO35
  • Links
    NCBI Gene ID: 285231
    neXtProt AC: NX_Q6X9E4
    UniProt: Q6X9E4

  • Chr Location
    3p21.31; chr3:48372219-48401259 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000105589 Ensembl Gene Model | MGI Sequence Detail 16887 C57BL/6J ±  kb
transcript ENSMUST00000198844 Ensembl | MGI Sequence Detail 1786 Not Applicable  
polypeptide ENSMUSP00000143404 Ensembl | MGI Sequence Detail 466 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR001810 F-box domain
    IPR036047 F-box-like domain superfamily
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139221
References
more
  • Summaries
    All 24
    Gene Ontology 1
  • Earliest
    J:58149 Winston JT, et al., A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory