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Slc25a5 Gene Detail
Summary
  • Symbol
    Slc25a5
  • Name
    solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
  • Synonyms
    adenine nucleotide translocase, Ant2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353496
    NCBI Gene: 11740
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:36059304-36062460 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 21.20 cM, cytoband A4
  • Mapping Data
    13 experiments
Strain
Comparison
more
  • SNPs within 2kb
    13 from dbSNP Build 142
  • Strain Annotations
    17
  • PCR
    2
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353496
 protein coding gene ChrX:36059250-36062461 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035624
 protein coding gene ChrX:31724664-31726978 (+)
A/J MGP_AJ_G0035601
 protein coding gene ChrX:31784467-31785741 (+)
AKR/J MGP_AKRJ_G0035534
 protein coding gene ChrX:32505578-32509089 (+)
BALB/cJ MGP_BALBcJ_G0035594
 protein coding gene ChrX:31527184-31530698 (+)
C3H/HeJ MGP_C3HHeJ_G0035312
 protein coding gene ChrX:32040485-32043680 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036130
 protein coding gene ChrX:32342418-32347027 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032992
 protein coding gene ChrX:30013985-30017124 (+)
CAST/EiJ MGP_CASTEiJ_G0028878
 protein coding gene Chr5:97030395-97031669 (+)
CBA/J MGP_CBAJ_G0035281
 protein coding gene ChrX:33205072-33207137 (+)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0035379
 protein coding gene ChrX:31384133-31387297 (+)
LP/J MGP_LPJ_G0016124
 protein coding gene Chr1:81878418-81879592 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035423
 protein coding gene ChrX:33659466-33660712 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036137
 protein coding gene ChrX:31689834-31694712 (+)
PWK/PhJ MGP_PWKPhJ_G0034304
 protein coding gene ChrX:19659101-19662235 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034145
 protein coding gene ChrX:20679643-20680856 (+)
WSB/EiJ MGP_WSBEiJ_G0034738
 protein coding gene ChrX:31485799-31486978 (+)



Homology
more
  • Human Ortholog
    SLC25A5, solute carrier family 25 member 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A5, solute carrier family 25 member 5
  • Synonyms
    2F1, AAC2, ANT2, T2, T3
  • Links
    NCBI Gene ID: 292
    neXtProt AC: NX_P05141
    UniProt: P05141

  • Chr Location
    Xq24; chrX:119468422-119471396 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    39
  • GO References
    17
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    772
  • Tissues
    64
  • cDNA Data
    18
  • Literature Summary
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016319 Ensembl Gene Model | MGI Sequence Detail 3157 C57BL/6J ±  kb
transcript ENSMUST00000016463 Ensembl | MGI Sequence Detail 1240 Not Applicable  
polypeptide ENSMUSP00000016463 Ensembl | MGI Sequence Detail 298 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    Genomic 4
    cDNA 19
    Primer pair 5

    Microarray probesets 11
Other
Accession IDs
less
MGD-MRK-33602, MGI:105924
References
more
  • Summaries
    All 68
    Developmental Gene Expression 11
    Gene Ontology 17
    Phenotypes 14
  • Earliest
    J:41737 Cozens AL, et al., DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. J Mol Biol. 1989 20;206(2):261-80
  • Latest
    J:339634 Bround MJ, et al., ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy. Sci Adv. 2023 Aug 25;9(34):eadi2767
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory