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Fam50a Gene Detail
Summary
  • Symbol
    Fam50a
  • Name
    family with sequence similarity 50, member A
  • Synonyms
    D0HXS9928E, XAP-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351626
    NCBI Gene: 108160
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:73356639-73363755 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351626
protein coding gene ChrX:73356589-73363761 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035841
protein coding gene ChrX:70112497-70119706 (+)
A/J MGP_AJ_G0035822
protein coding gene ChrX:70297514-70304365 (+)
AKR/J MGP_AKRJ_G0035747
protein coding gene ChrX:72199147-72206189 (+)
BALB/cJ MGP_BALBcJ_G0035807
protein coding gene ChrX:69324085-69331390 (+)
C3H/HeJ MGP_C3HHeJ_G0035512
protein coding gene ChrX:70587326-70595286 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036337
protein coding gene ChrX:72274977-72282819 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033181
protein coding gene ChrX:69363583-69370287 (+)
CAST/EiJ MGP_CASTEiJ_G0034803
protein coding gene ChrX:55970040-55976926 (+)
CBA/J MGP_CBAJ_G0035487
protein coding gene ChrX:74273517-74280376 (+)
DBA/2J MGP_DBA2J_G0035644
protein coding gene ChrX:69757344-69764237 (+)
FVB/NJ MGP_FVBNJ_G0035588
protein coding gene ChrX:69101479-69108359 (+)
LP/J MGP_LPJ_G0035729
protein coding gene ChrX:70891809-70898912 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035626
protein coding gene ChrX:76834991-76841909 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036359
protein coding gene ChrX:69930087-69937912 (+)
PWK/PhJ MGP_PWKPhJ_G0034502
protein coding gene ChrX:53929366-53936290 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034336
protein coding gene ChrX:56836627-56843498 (+)
WSB/EiJ MGP_WSBEiJ_G0034944
protein coding gene ChrX:69214733-69221776 (+)



Homology
more
  • Human Ortholog
    FAM50A, family with sequence similarity 50 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM50A, family with sequence similarity 50 member A
  • Synonyms
    9F, DXS9928E, HXC26, HXC-26, MRXSA, XAP5
  • Links
    NCBI Gene ID: 9130
    neXtProt AC: NX_Q14320
    UniProt: Q14320

  • Chr Location
    Xq28; chrX:154444141-154450654 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human FAM50A associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001962 Ensembl Gene Model | MGI Sequence Detail 7117 C57BL/6J ±  kb
transcript ENSMUST00000114160 Ensembl | MGI Sequence Detail 1383 Not Applicable  
polypeptide ENSMUSP00000109797 Ensembl | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:58261 Sedlacek Z, et al., Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of an ancient functional retroposon differentially expressed in testis. Genomics. 1999 Oct 15;61(2):125-32
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory