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Xlr5c Gene Detail
Summary
  • Symbol
    Xlr5c
  • Name
    X-linked lymphocyte-regulated 5C
  • Synonyms
    Xlr5
Location &
Maps
more
  • Sequence Map
    ChrX:72326502-72336582 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.29 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    144 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1350981
protein coding gene ChrX:72326502-72337469 (-)
129S1/SvImJ no annotation
A/J ENSMUSG00195033168
protein coding gene ChrX:58070725-58080805 (-)
AKR/J ENSMUSG00220042420
protein coding gene ChrX:53373032-53383112 (-)
BALB/cJ ENSMUSG00180046984
protein coding gene ChrX:54651466-54661546 (-)
C3H/HeJ ENSMUSG00175031558
protein coding gene ChrX:58235150-58245230 (-)
C57BL/6NJ ENSMUSG00215041122
protein coding gene ChrX:54727469-54737549 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J ENSMUSG00210041471
protein coding gene ChrX:54915825-54925905 (-)
DBA/2J ENSMUSG00185032873
protein coding gene ChrX:67337469-67347549 (-)
FVB/NJ ENSMUSG00205022107
protein coding gene ChrX:54216634-54226713 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230036508
protein coding gene ChrX:73908882-73918962 (-)
NOD/ShiLtJ ENSMUSG00190042060
protein coding gene ChrX:54155832-54165912 (-)
NZO/HlLtJ ENSMUSG00225048110
protein coding gene ChrX:79113228-79123308 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    FAM9A, family with sequence similarity 9 member A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM9A, family with sequence similarity 9 member A
  • Synonyms
    TEX39A
  • Links
    NCBI Gene ID: 171482
    UniProt: Q8IZU1

  • Chr Location
    Xp22.31; chrX:8790795-8801383 (-)  GRCh38

  • Human Ortholog
    FAM9C, family with sequence similarity 9 member C
  • Synonyms
    TEX39C
  • Links
    NCBI Gene ID: 171484
    UniProt: Q8IZT9

  • Chr Location
    Xp22.2; chrX:13035617-13044682 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067764 Ensembl Gene Model | MGI Sequence Detail 10081 C57BL/6J ±  kb
transcript ENSMUST00000114503 Ensembl | MGI Sequence Detail 1656 Not Applicable  
polypeptide ENSMUSP00000110147 Ensembl | MGI Sequence Detail 236 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR051443 X-linked Lymphocyte-regulated/Synaptonemal Complex Protein 3
    IPR006888 XLR/SYCP3/FAM9 domain
Molecular
Reagents
less
  • All nucleic 7
    Genomic 1
    cDNA 5
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:33576 Levin ML, et al., A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 Jun;6(6):465-77
  • Latest
    J:237817 Zhuang XJ, et al., Identification and Characterization of Xlr5c as a Novel Nuclear Localization Protein in Mouse Germ Cells. PLoS One. 2015;10(6):e0130087

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/01/2026
MGI 6.24
The Jackson Laboratory