Ifi202b Gene Detail

Summary

• Symbol
  Ifi202b
• Name
  interferon activated gene 202B
• Synonyms
  p202

• Feature Type
  protein coding gene
• IDs
  MGI:1347083
  NCBI Gene: 26388
• Alliance
  genome feature page
• Transcription Start Sites
  21 TSS

Location &
Maps

• Sequence Map
  Chr1:173790134-173810310 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 1, 80.79 cM
• Mapping Data
  4 experiments

Strain
Comparison

• SNPs within 2kb
  19 from dbSNP Build 142
• Strain Annotations
  16

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1347083	protein coding gene	Chr1:173790134-173810410 (-)
129S1/SvImJ	ENSMUSG00200043186	protein coding gene	Chr1:171646031-171664255 (-)
A/J	ENSMUSG00195044842	protein coding gene	Chr1:170911464-170939098 (-)
AKR/J	ENSMUSG00220025293	protein coding gene	Chr1:170634030-170670805 (-)
BALB/cJ	ENSMUSG00180043765	protein coding gene	Chr1:171223927-171242151 (-)
C3H/HeJ	ENSMUSG00175045579	protein coding gene	Chr1:171400166-171418390 (-)
C57BL/6NJ	ENSMUSG00215042019	protein coding gene	Chr1:170750706-170770876 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005044223	protein coding gene	Chr1:169339644-169359729 (-)
CBA/J	ENSMUSG00210033219	protein coding gene	Chr1:170987804-171004350 (-)
DBA/2J	ENSMUSG00185028984	protein coding gene	Chr1:175412521-175512816 (-)
FVB/NJ	ENSMUSG00205021555	protein coding gene	Chr1:170131027-170158662 (-)
JF1/MsJ	ENSUMUG00000012376	protein coding gene	Chr1:174465215-174485384 (-)
LP/J	no annotation
NOD/ShiLtJ	ENSMUSG00190034538	protein coding gene	Chr1:171075613-171093837 (-)
NZO/HlLtJ	ENSMUSG00225004663	protein coding gene	Chr1:178586824-178733260 (-)
PWK/PhJ	ENSLUMG00010028732	protein coding gene	Chr1:169740789-169794957 (-)
SPRET/EiJ	no annotation
WSB/EiJ	ENSIUOG00005035892	protein coding gene	Chr1:170219208-170243097 (-)

Homology

• Human Ortholog
  IFI16, interferon gamma inducible protein 16

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  IFI16, interferon gamma inducible protein 16
  
• Synonyms
  IFNGIP1, PYHIN2
• Links
  HGNC:5395

  NCBI Gene ID: 3428

  UniProt: Q16666

  
  
• Chr Location
  1q23.1; chr1:158999953-159055156 (+)  GRCh38

---

• Human Ortholog
  PYHIN1, pyrin and HIN domain family member 1
  
• Synonyms
  IFIX
• Links
  HGNC:28894

  NCBI Gene ID: 149628

  UniProt: Q6K0P9

  
  
• Chr Location
  1q23.1; chr1:158930796-158990870 (+)  GRCh38

---

• MGI Vertebrate Homology
  Ifi202b stringent orthology
  2 human;1 mouse
  
• HCOP
  vertebrate homology predictions: IFI16, PYHIN1
• Gene Tree
  Ifi202b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  15 phenotype references
  

• All Mutations and Alleles
  8
• Chemically induced (other)
  2
• Endonuclease-mediated
  2
• Spontaneous
  1
• Targeted
  3
• Genomic Mutations
  3 involving Ifi202b
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  19 strains or lines available

A spontaneous null mutation carried by C57BL/6J mice may result in resistance to obesity.

Expression

• Assay Results
  611
• Tissues
  6
• cDNA Data
  4
• Literature Summary
  5

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  34
• RefSeq
  4
• UniProt
  1
• CCDS
  CCDS35794.1

• Ensembl
  ENSMUSG00000026535 (Evidence)
• NCBI Gene
  26388

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000026535	Ensembl Gene Model | MGI Sequence Detail	20177	C57BL/6J
transcript	ENSMUST00000000266	Ensembl | MGI Sequence Detail	1697	Not Applicable
polypeptide	ENSMUSP00000000266	Ensembl | MGI Sequence Detail	445	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 7

  Genomic 1

  cDNA 4

  Primer pair 1

  Other 1

  Antibodies 2

  
  

  Microarray probesets 2

References

• Summaries
  All 72

  Developmental Gene Expression 5

  Phenotypes 15
• Earliest
  J:10055 Choubey D, et al., Interferons as gene activators. Indications for repeated gene duplication during the evolution of a cluster of interferon-activatable genes on murine chromosome 1. J Biol Chem. 1989 Oct 15;264(29):17182-9
• Latest
  J:359312 Jena KK, et al., Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair. Cell. 2024 Nov 4;

TSS for Ifi202b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr15370	Chr1:173810408-173810414 (-)	-101 bp
Tssr15369	Chr1:173809826-173809852 (-)	471 bp
Tssr15368	Chr1:173807589-173807600 (-)	2,715 bp
Tssr15367	Chr1:173807487-173807500 (-)	2,816 bp
Tssr15366	Chr1:173807469-173807481 (-)	2,835 bp
Tssr15365	Chr1:173807451-173807462 (-)	2,853 bp
Tssr15364	Chr1:173807396-173807407 (-)	2,908 bp
Tssr15363	Chr1:173807323-173807337 (-)	2,980 bp
Tssr15362	Chr1:173807179-173807210 (-)	3,115 bp
Tssr15361	Chr1:173807054-173807069 (-)	3,248 bp
Tssr15360	Chr1:173806999-173807016 (-)	3,302 bp
Tssr15359	Chr1:173804892-173804907 (-)	5,410 bp
Tssr15358	Chr1:173804852-173804868 (-)	5,450 bp
Tssr15357	Chr1:173804518-173804543 (-)	5,779 bp
Tssr15356	Chr1:173802629-173802687 (-)	7,652 bp
Tssr306	Chr1:173802612-173802622 (-)	7,693 bp
Tssr15355	Chr1:173802530-173802605 (-)	7,742 bp
Tssr15354	Chr1:173802419-173802496 (-)	7,852 bp
Tssr15353	Chr1:173799273-173799297 (-)	11,025 bp
Tssr15352	Chr1:173798910-173798923 (-)	11,393 bp
Tssr15351	Chr1:173791470-173791490 (-)	18,830 bp