Ifi202a Gene Detail

Summary

• Symbol
  Ifi202a
• Name
  interferon activated gene 202A
• Synonyms
  Ifbip-1, Ifi202

• Feature Type
  protein coding gene
• IDs
  MGI:1347080
• Alliance
  genome feature page
• Transcription Start Sites
  10 TSS
• Candidate for QTL
  4 QTL

Location &
Maps

• Sequence Map
  Chr1:173790141-173859357 bp, - strand

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 1, Syntenic
• Mapping Data
  13 experiments

Strain
Comparison

• SNPs within 2kb
  589 from dbSNP Build 142
• RFLP
  6

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	no annotation
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

Homozyous mutants have no apperent defects.

Expression

• cDNA Data
  6
• Literature Summary
  1

Sequences &
Gene Models

• All Sequences
  5
• UniProt
  1

Representative Sequences			Length	Strain/Species
genomic	M31422	GenBank | ENA | DDBJ | MGI Sequence Detail	958	Not Specified
transcript	M31418	GenBank | ENA | DDBJ | MGI Sequence Detail	1857	Not Specified
polypeptide	Q9R002	UniProt | EBI | MGI Sequence Detail	445	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 17

  Genomic 9

  cDNA 8

  
  

  Microarray probesets 1

Other
Accession IDs

MGD-MRK-11213, MGD-MRK-11220, MGI:96427

References

• Summaries
  All 26

  Developmental Gene Expression 1

  Phenotypes 1
• Earliest
  J:7514 Samanta H, et al., Chromosomal location of mouse gene 202 which is induced by interferons and specifies a 56.5 kD protein. J Interferon Res. 1984 Spring;4(2):295-300
• Latest
  J:153284 Zhang K, et al., Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility. Blood. 2009 Oct 1;114(14):2952-60

TSS for Ifi202a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr15380	Chr1:173859345-173859355 (-)	7 bp
Tssr15379	Chr1:173859278-173859294 (-)	71 bp
Tssr15378	Chr1:173856043-173856055 (-)	3,308 bp
Tssr15377	Chr1:173856018-173856028 (-)	3,334 bp
Tssr15376	Chr1:173855981-173855994 (-)	3,369 bp
Tssr15375	Chr1:173855933-173855944 (-)	3,418 bp
Tssr15374	Chr1:173855865-173855876 (-)	3,486 bp
Tssr15373	Chr1:173855836-173855845 (-)	3,516 bp
Tssr15372	Chr1:173854865-173854890 (-)	4,479 bp
Tssr15371	Chr1:173851966-173852004 (-)	7,372 bp

Ifi202a is Candidate Gene for:

QTL	Genetic Location*	Genome Location (GRCm39)	Reference	QTL Note
Lmr20	Chr1, syntenic	Chr1:175468817-175468938	J:152405	Potential candidated genes mapping near Lmr20, Lmr20a, Lmr20b and Lmr20c which mapped to D1Mit403 at 100.0 cM of CcS11/Dem in this study are: Fcer1a, Fc receptor, IgE, high affinity I, alpha polypeptide at 94.2 cM; Fcer1g, Fc receptor, IgE, high affinity I, gamma polypeptide at 93.3 cM; Fcgr2b, Fc receptor, IgG, low affinity IIb at 92.3 cM; Cluster of IFN activated genes: Ifi201,Ifi202a; Ifi203, and Ifi204 between 95.2-95.3 cM; and Tgfb2, transforming growth factor, beta 2 at 101.5 cM. [Table 9.] Possibly related QTL controlling other infections and co-localizing with the Lmr20 QTL are: Tir3c, trypanosome infection response 3c at 93.0 cM; Ssta2, susceptibility to Salmonella typhimurium antigens 2 at 95.8 cM; Bbaa12, B.burgdorferi-associated arthritis 12 at 96.0 cM; and, Berr1, berghei resistance locus 1 at 102.0 cM; [Table 10].
Lmr20a	Chr1, syntenic	Chr1:175468817-175468938	J:152405	Potential candidated genes mapping near Lmr20, Lmr20a, Lmr20b and Lmr20c which mapped to D1Mit403 at 100.0 cM of CcS11/Dem in this study are: Fcer1a, Fc receptor, IgE, high affinity I, alpha polypeptide at 94.2 cM; Fcer1g, Fc receptor, IgE, high affinity I, gamma polypeptide at 93.3 cM; Fcgr2b, Fc receptor, IgG, low affinity IIb at 92.3 cM; Cluster of IFN activated genes: Ifi201,Ifi202a; Ifi203, and Ifi204 between 95.2-95.3 cM; and Tgfb2, transforming growth factor, beta 2 at 101.5 cM. [Table 9.] Possibly related QTL controlling other infections and co-localizing with the Lmr20 QTL are: Tir3c, trypanosome infection response 3c at 93.0 cM; Ssta2, susceptibility to Salmonella typhimurium antigens 2 at 95.8 cM; Bbaa12, B.burgdorferi-associated arthritis 12 at 96.0 cM; and, Berr1, berghei resistance locus 1 at 102.0 cM; [Table 10].
Lmr20b	Chr1, syntenic	Chr1:175468817-175468938	J:152405	Potential candidated genes mapping near Lmr20, Lmr20a, Lmr20b and Lmr20c which mapped to D1Mit403 at 100.0 cM of CcS11/Dem in this study are: Fcer1a, Fc receptor, IgE, high affinity I, alpha polypeptide at 94.2 cM; Fcer1g, Fc receptor, IgE, high affinity I, gamma polypeptide at 93.3 cM; Fcgr2b, Fc receptor, IgG, low affinity IIb at 92.3 cM; Cluster of IFN activated genes: Ifi201,Ifi202a; Ifi203, and Ifi204 between 95.2-95.3 cM; and Tgfb2, transforming growth factor, beta 2 at 101.5 cM. [Table 9.] Possibly related QTL controlling other infections and co-localizing with the Lmr20 QTL are: Tir3c, trypanosome infection response 3c at 93.0 cM; Ssta2, susceptibility to Salmonella typhimurium antigens 2 at 95.8 cM; Bbaa12, B.burgdorferi-associated arthritis 12 at 96.0 cM; and, Berr1, berghei resistance locus 1 at 102.0 cM; [Table 10].
Lmr20c	Chr1, syntenic	Chr1:175468817-175468938	J:152405	Potential candidated genes mapping near Lmr20, Lmr20a, Lmr20b and Lmr20c which mapped to D1Mit403 at 100.0 cM of CcS11/Dem in this study are: Fcer1a, Fc receptor, IgE, high affinity I, alpha polypeptide at 94.2 cM; Fcer1g, Fc receptor, IgE, high affinity I, gamma polypeptide at 93.3 cM; Fcgr2b, Fc receptor, IgG, low affinity IIb at 92.3 cM; Cluster of IFN activated genes: Ifi201,Ifi202a; Ifi203, and Ifi204 between 95.2-95.3 cM; and Tgfb2, transforming growth factor, beta 2 at 101.5 cM. [Table 9.] Possibly related QTL controlling other infections and co-localizing with the Lmr20 QTL are: Tir3c, trypanosome infection response 3c at 93.0 cM; Ssta2, susceptibility to Salmonella typhimurium antigens 2 at 95.8 cM; Bbaa12, B.burgdorferi-associated arthritis 12 at 96.0 cM; and, Berr1, berghei resistance locus 1 at 102.0 cM; [Table 10].

*cM position of peak correlated region/marker