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Scamp2 Gene Detail
Summary
  • Symbol
    Scamp2
  • Name
    secretory carrier membrane protein 2
  • Synonyms
    Sc2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346518
    NCBI Gene: 24044
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:57468226-57496078 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 31.05 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    636 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346518
 protein coding gene Chr9:57468226-57496081 (+)
129S1/SvImJ ENSMUSG00200032277
 protein coding gene Chr9:54593787-54621640 (+)
A/J ENSMUSG00195037518
 protein coding gene Chr9:54293944-54321803 (+)
AKR/J ENSMUSG00220026696
 protein coding gene Chr9:54434770-54462634 (+)
BALB/cJ ENSMUSG00180016172
 protein coding gene Chr9:54407547-54435403 (+)
C3H/HeJ ENSMUSG00175021590
 protein coding gene Chr9:54420756-54448614 (+)
C57BL/6NJ ENSMUSG00215017154
 protein coding gene Chr9:54400903-54428756 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032273
 protein coding gene Chr9:54251049-54277875 (+)
CAST/EiJ ENSTCUG00005018504
 protein coding gene Chr9:54324386-54352415 (+)
CBA/J ENSMUSG00210035655
 protein coding gene Chr9:54529034-54556885 (+)
DBA/2J ENSMUSG00185042799
 protein coding gene Chr9:54551257-54579121 (+)
FVB/NJ ENSMUSG00205021273
 protein coding gene Chr9:54858031-54885897 (+)
JF1/MsJ ENSUMUG00000025007
 protein coding gene Chr9:54567780-54595672 (+)
LP/J ENSMUSG00230037575
 protein coding gene Chr9:54793568-54821423 (+)
NOD/ShiLtJ ENSMUSG00190032800
 protein coding gene Chr9:54619274-54647137 (+)
NZO/HlLtJ ENSMUSG00225027608
 protein coding gene Chr9:54832329-54860185 (+)
PWK/PhJ ENSLUMG00010038047
 protein coding gene Chr9:54522883-54550767 (+)
SPRET/EiJ ENSMSPG00010024118
 protein coding gene Chr9:55568322-55594656 (+)
WSB/EiJ ENSIUOG00005033962
 protein coding gene Chr9:54033140-54060996 (+)



Homology
more
  • Human Ortholog
    SCAMP2, secretory carrier membrane protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCAMP2, secretory carrier membrane protein 2
  • Links
    NCBI Gene ID: 10066
    UniProt: O15127

  • Chr Location
    15q24.1; chr15:74843728-74873374 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    18
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040188 Ensembl Gene Model | MGI Sequence Detail 27853 C57BL/6J ±  kb
    transcript ENSMUST00000045791 Ensembl | MGI Sequence Detail 2340 Not Applicable  
    polypeptide ENSMUSP00000038350 Ensembl | MGI Sequence Detail 329 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2143165
    References
    more
    • Summaries
      All 39
      Gene Ontology 6
      Phenotypes 11
    • Earliest
      J:43149 Singleton DR, et al., Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions. J Cell Sci. 1997 Sep;110(Pt 17):2099-107
    • Latest
      J:367686 Briere A, et al., Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies. Invest Ophthalmol Vis Sci. 2025 May 1;66(5):7
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory