Cdh20 MGI Mouse Gene Detail - MGI:1346069

Symbol

Cdh20
Name

cadherin 20
Synonyms

Cdh7

Feature Type

protein coding gene
IDs

MGI:1346069
NCBI Gene: 23836
Alliance

genome feature page
Transcription Start Sites

4 TSS

Sequence Map

Chr1:104696254-104923206 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 49.42 cM
Mapping Data

1 experiment

SNPs within 2kb

6375 from dbSNP Build 142
Strain Annotations

19
PCR

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1346069	protein coding gene	Chr1:104696245-104923206 (+)
129S1/SvImJ	ENSMUSG00200000319	protein coding gene	Chr1:101975102-102198717 (+)
A/J	ENSMUSG00195007640	protein coding gene	Chr1:101446292-101669530 (+)
AKR/J	ENSMUSG00220000156	protein coding gene	Chr1:101517793-101741079 (+)
BALB/cJ	ENSMUSG00180000275	protein coding gene	Chr1:101733634-101956845 (+)
C3H/HeJ	ENSMUSG00175000546	protein coding gene	Chr1:101639765-101862994 (+)
C57BL/6NJ	ENSMUSG00215006613	protein coding gene	Chr1:101683160-101910256 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014481	protein coding gene	Chr1:97542285-97761250 (+)
CAST/EiJ	ENSTCUG00005000085	protein coding gene	Chr1:101046110-101275895 (+)
CBA/J	ENSMUSG00210000043	protein coding gene	Chr1:101533754-101756982 (+)
DBA/2J	ENSMUSG00185007992	protein coding gene	Chr1:106001414-106225019 (+)
FVB/NJ	ENSMUSG00205000729	protein coding gene	Chr1:100833287-101056538 (+)
JF1/MsJ	ENSUMUG00000000133	protein coding gene	Chr1:104628493-104866228 (+)
LP/J	ENSMUSG00230000052	protein coding gene	Chr1:105264360-105487926 (+)
NOD/ShiLtJ	ENSMUSG00190000226	protein coding gene	Chr1:101631095-101854676 (+)
NZO/HlLtJ	ENSMUSG00225000303	protein coding gene	Chr1:109138453-109361726 (+)
PWK/PhJ	ENSLUMG00010006325	protein coding gene	Chr1:101061916-101286327 (+)
SPRET/EiJ	ENSMSPG00010000445	protein coding gene	Chr1:103315133-103543586 (+)
WSB/EiJ	ENSIUOG00005000979	protein coding gene	Chr1:101340149-101562588 (+)

Human Ortholog

CDH20, cadherin 20

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CDH20, cadherin 20
Synonyms

Cdh7, CDH7L3
Links

HGNC:1760

NCBI Gene ID: 28316

UniProt: Q9HBT6
Chr Location

18q21.33; chr18:61333430-61555779 (+) GRCh38

MGI Vertebrate Homology

Cdh20 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CDH20
Gene Tree

Cdh20

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Chemically induced (other)

2
Endonuclease-mediated

1
Radiation induced

1
Targeted

2
Genomic Mutations

3 involving Cdh20
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

54 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

18
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

857
Tissues

200
cDNA Data

13
Literature Summary

14

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

GEISHA CDH20

Xenbase cdh20

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All Sequences

32
RefSeq

4
UniProt

1
CCDS

CCDS15203.1

Ensembl

ENSMUSG00000050840 (Evidence)
NCBI Gene

23836

			Length	Strain/Species	Flank
genomic	ENSMUSG00000050840	Ensembl Gene Model \| MGI Sequence Detail	226953	C57BL/6J	± kb
transcript	ENSMUST00000062528	Ensembl \| MGI Sequence Detail	4012	Not Applicable
polypeptide	ENSMUSP00000052078	Ensembl \| MGI Sequence Detail	801	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000005238 cadherin-20

(term hierarchy)
InterPro Domains

IPR039808 Cadherin

IPR020894 Cadherin conserved site

IPR002126 Cadherin-like

IPR015919 Cadherin-like superfamily

IPR000233 Cadherin, Y-type LIR-motif

IPR027397 Catenin binding domain superfamily
GlyGen

Q9Z0M3 6 sites, 3 N-linked glycans (3 sites), 1 O-linked glycan (2 sites)

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All nucleic 20

cDNA 13

Primer pair 5

Other 2

Microarray probesets 2

Summaries

All 42

Developmental Gene Expression 14

Gene Ontology 4

Phenotypes 10
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:353444 Bessa P, et al., Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring. Nat Commun. 2024 Aug 16;15(1):7059

TSS for Cdh20:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr8250	Chr1:104696235-104696251 (+)	-11 bp
Tssr8251	Chr1:104696321-104696333 (+)	73 bp
Tssr8252	Chr1:104696521-104696548 (+)	281 bp
Tssr8253	Chr1:104708648-104708651 (+)	12,396 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/01/2026 MGI 6.24