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Gdap2 Gene Detail
Summary
  • Symbol
    Gdap2
  • Name
    ganglioside-induced differentiation-associated-protein 2
  • Synonyms
    D3Ertd801e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338001
    NCBI Gene: 14547
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:100069697-100114297 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 43.49 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    379 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338001
protein coding gene Chr3:100069697-100117909 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027666
protein coding gene Chr3:101283121-101330679 (+)
A/J MGP_AJ_G0027625
protein coding gene Chr3:98063850-98112325 (+)
AKR/J MGP_AKRJ_G0027591
protein coding gene Chr3:100438817-100485996 (+)
BALB/cJ MGP_BALBcJ_G0027638
protein coding gene Chr3:97841498-97886359 (+)
C3H/HeJ MGP_C3HHeJ_G0027367
protein coding gene Chr3:100757519-100803538 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028081
protein coding gene Chr3:105002587-105048533 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025422
protein coding gene Chr3:94290089-94334920 (+)
CAST/EiJ MGP_CASTEiJ_G0026823
protein coding gene Chr3:99873313-99919314 (+)
CBA/J MGP_CBAJ_G0027342
protein coding gene Chr3:108622803-108668443 (+)
DBA/2J MGP_DBA2J_G0027485
protein coding gene Chr3:97312756-97359351 (+)
FVB/NJ MGP_FVBNJ_G0027453
protein coding gene Chr3:95266233-95311126 (+)
LP/J MGP_LPJ_G0027592
protein coding gene Chr3:102621023-102670612 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0028136
protein coding gene Chr3:99943272-99993146 (+)
PWK/PhJ MGP_PWKPhJ_G0026550
protein coding gene Chr3:97068947-97114438 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026372
protein coding gene Chr3:98064012-98113239 (+)
WSB/EiJ MGP_WSBEiJ_G0026903
protein coding gene Chr3:100523082-100567252 (+)



Homology
more
  • Human Ortholog
    GDAP2, ganglioside induced differentiation associated protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GDAP2, ganglioside induced differentiation associated protein 2
  • Synonyms
    MACROD3, SCAR27
  • Links
    NCBI Gene ID: 54834
    neXtProt AC: NX_Q9NXN4
    UniProt: Q9NXN4

  • Chr Location
    1p12; chr1:117863485-117929621 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human GDAP2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027865 Ensembl Gene Model | MGI Sequence Detail 44601 C57BL/6J ±  kb
    transcript ENSMUST00000106997 Ensembl | MGI Sequence Detail 2014 Not Applicable  
    polypeptide ENSMUSP00000102610 Ensembl | MGI Sequence Detail 546 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 61
      cDNA 59
      Primer pair 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1289278, MGI:2140042
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 1
      Phenotypes 12
    • Earliest
      J:54635 Liu H, et al., Isolation of 10 differentially expressed cDNAs in differentiated Neuro2a cells induced through controlled expression of the GD3 synthase gene. J Neurochem. 1999 May;72(5):1781-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    06/12/2024
    MGI 6.13
    The Jackson Laboratory