Krtap6-2 Gene Detail

Summary

• Symbol
  Krtap6-2
• Name
  keratin associated protein 6-2

• Feature Type
  protein coding gene
• IDs
  MGI:1330280
  NCBI Gene: 16701
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr16:89216214-89216999 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, 51.42 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  117 from dbSNP Build 142
• Strain Annotations
  16

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1330280	protein coding gene	Chr16:89216211-89216999 (-)
129S1/SvImJ	ENSMUSG00200036745	protein coding gene	Chr16:86098478-86099263 (-)
A/J	ENSMUSG00195028618	protein coding gene	Chr16:85895588-85896373 (-)
AKR/J	ENSMUSG00220015277	protein coding gene	Chr16:86085714-86086499 (-)
BALB/cJ	ENSMUSG00180014952	protein coding gene	Chr16:85968795-85969580 (-)
C3H/HeJ	ENSMUSG00175014098	protein coding gene	Chr16:86307015-86307800 (-)
C57BL/6NJ	ENSMUSG00215026217	protein coding gene	Chr16:86097112-86097897 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020938	protein coding gene	Chr16:83833541-83834225 (-)
CAST/EiJ	no annotation
CBA/J	ENSMUSG00210032168	protein coding gene	Chr16:86196546-86197331 (-)
DBA/2J	ENSMUSG00185029372	protein coding gene	Chr16:86147840-86148625 (-)
FVB/NJ	ENSMUSG00205012888	protein coding gene	Chr16:85942311-85943096 (-)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230032497	protein coding gene	Chr16:88645793-88646578 (-)
NOD/ShiLtJ	ENSMUSG00190019673	protein coding gene	Chr16:86123292-86124077 (-)
NZO/HlLtJ	ENSMUSG00225030688	protein coding gene	Chr16:91820140-91820925 (-)
PWK/PhJ	ENSLUMG00010013494	protein coding gene	Chr16:85893937-85894722 (-)
SPRET/EiJ	no annotation
WSB/EiJ	ENSIUOG00005018766	protein coding gene	Chr16:86052660-86053445 (-)

Homology

• Gene Tree
  Krtap6-2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotype references
  

• All Mutations and Alleles
  6
• Endonuclease-mediated
  2
• Targeted
  3
• Genomic Mutations
  3 involving Krtap6-2
• Find Mice (IMSR)
  18 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  597
• cDNA Data
  9

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  32
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS79482.1

• Ensembl
  ENSMUSG00000062433 (Evidence)
• NCBI Gene
  16701

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000062433	Ensembl Gene Model | MGI Sequence Detail	786	C57BL/6J
transcript	ENSMUST00000082065	Ensembl | MGI Sequence Detail	786	Not Applicable
polypeptide	ENSMUSP00000139661	Ensembl | MGI Sequence Detail	155	Not Applicable

Protein
Information

• UniProt
  2 Sequences

Molecular
Reagents

• All nucleic 9

  cDNA 9

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:2146469

References

• Summaries
  All 30

  Gene Ontology 1

  Phenotypes 9
• Earliest
  J:44334 Aoki N, et al., Isolation and characterization of mouse high-glycine/tyrosine proteins. J Biol Chem. 1997 Nov 28;272(48):30512-8
• Latest
  J:361105 Tateossian H, et al., DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome. Elife. 2025;

TSS for Krtap6-2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr141986	Chr16:89217015-89217022 (-)	-20 bp