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Prkx Gene Detail
Summary
  • Symbol
    Prkx
  • Name
    protein kinase, X-linked
  • Synonyms
    Pkare
  • Feature Type
    protein coding gene
  • IDs
    MGI:1309999
    NCBI Gene: 19108
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:76805017-76839884 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 38.32 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1309999
 protein coding gene ChrX:76804578-76839884 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035870
 protein coding gene ChrX:73581600-73621962 (-)
A/J MGP_AJ_G0035857
 protein coding gene ChrX:73876672-73912974 (-)
AKR/J MGP_AKRJ_G0035777
 protein coding gene ChrX:75789788-75827956 (-)
BALB/cJ MGP_BALBcJ_G0035837
 protein coding gene ChrX:72812232-72847411 (-)
C3H/HeJ MGP_C3HHeJ_G0035549
 protein coding gene ChrX:74083495-74120790 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036369
 protein coding gene ChrX:75941450-75978269 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033203
 protein coding gene ChrX:73154414-73191339 (-)
CAST/EiJ MGP_CASTEiJ_G0034838
 protein coding gene ChrX:59345752-59380301 (-)
CBA/J MGP_CBAJ_G0035522
 protein coding gene ChrX:77942589-77982515 (-)
DBA/2J MGP_DBA2J_G0035679
 protein coding gene ChrX:73298401-73335442 (-)
FVB/NJ MGP_FVBNJ_G0035620
 protein coding gene ChrX:72566426-72604168 (-)
LP/J MGP_LPJ_G0035765
 protein coding gene ChrX:74474085-74510038 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035655
 protein coding gene ChrX:80699782-80739835 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036394
 protein coding gene ChrX:73441360-73478605 (-)
PWK/PhJ MGP_PWKPhJ_G0034534
 protein coding gene ChrX:57403523-57439153 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034368
 protein coding gene ChrX:60164571-60199378 (-)
WSB/EiJ MGP_WSBEiJ_G0034974
 protein coding gene ChrX:72633726-72672101 (-)



Homology
more
  • Human Ortholog
    PRKX, protein kinase cAMP-dependent X-linked catalytic subunit
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRKX, protein kinase cAMP-dependent X-linked catalytic subunit
  • Synonyms
    PKX1
  • Links
    NCBI Gene ID: 5613
    neXtProt AC: NX_P51817
    UniProt: P51817

  • Chr Location
    Xp22.33; chrX:3604340-3713649 (-)  GRCh38
  • Human Ortholog
    PRKY, protein kinase Y-linked (pseudogene)
  • Synonyms
    PRKXP3, PRKYP
  • Links
    NCBI Gene ID: 5616
    UniProt: O43930

  • Chr Location
    Yp11.2; chrY:7273972-7381547 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    761
  • Tissues
    51
  • cDNA Data
    67
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035725 Ensembl Gene Model | MGI Sequence Detail 34868 C57BL/6J ±  kb
transcript ENSMUST00000036333 Ensembl | MGI Sequence Detail 4146 Not Applicable  
polypeptide ENSMUSP00000045304 Ensembl | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 71
    Genomic 1
    cDNA 69
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 4
  • Earliest
    J:45217 Blaschke RJ, et al., Man to mouse--lessons learned from the distal end of the human X chromosome. Genome Res. 1997 Dec;7(12):1114-7
  • Latest
    J:320677 Piazzon N, et al., Bicc1 links the regulation of cAMP signaling in polycystic kidneys to microRNA-induced gene silencing. J Mol Cell Biol. 2012 Dec;4(6):398-408
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory