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Serpinb3c Gene Detail
Summary
  • Symbol
    Serpinb3c
  • Name
    serine (or cysteine) peptidase inhibitor, clade B, member 3C
  • Synonyms
    1110001H02Rik, 1110013A16Rik, ovalbumin, Scca2, Serpinb4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277952
    NCBI Gene: 381286
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr1:107198931-107206101 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 50.34 cM, cytoband E1-E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    40 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277952
 protein coding gene Chr1:107198931-107206101 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016379
 protein coding gene Chr1:109487011-109493897 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0016323
 protein coding gene Chr1:108598478-108605101 (-)
BALB/cJ MGP_BALBcJ_G0016319
 protein coding gene Chr1:105789333-105799276 (-)
C3H/HeJ MGP_C3HHeJ_G0016146
 protein coding gene Chr1:109013148-109019358 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016778
 protein coding gene Chr1:113659995-113668441 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014496
 protein coding gene Chr1:99744828-99752007 (-)
CAST/EiJ MGP_CASTEiJ_G0015729
 protein coding gene Chr1:107943037-107948255 (-)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0016225
 protein coding gene Chr1:104719292-104727532 (-)
FVB/NJ MGP_FVBNJ_G0016224
 protein coding gene Chr1:103672836-103679706 (-)
LP/J MGP_LPJ_G0016298
 protein coding gene Chr1:110776599-110784229 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016251
 protein coding gene Chr1:121969781-121978090 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0015300
 protein coding gene Chr1:107041733-107048391 (-)
WSB/EiJ MGP_WSBEiJ_G0015791
 protein coding gene Chr1:108484108-108487964 (-)



Homology
more
  • Human Ortholog
    SERPINB3, serpin family B member 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERPINB3, serpin family B member 3
  • Synonyms
    HsT1196, SCC, SCCA1, SCCA-1, SCCA-PD, SSCA1, T4-A
  • Links
    NCBI Gene ID: 6317
    neXtProt AC: NX_P29508
    UniProt: P29508

  • Chr Location
    18q21.33; chr18:63655197-63661893 (-)  GRCh38
  • Human Ortholog
    SERPINB4, serpin family B member 4
  • Synonyms
    LEUPIN, PI11, SCCA1, SCCA2, SCCA-2
  • Links
    NCBI Gene ID: 6318
    neXtProt AC: NX_P48594
    UniProt: P48594

  • Chr Location
    18q21.33; chr18:63637259-63644256 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Serpinb3c
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    28 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    726
  • Tissues
    14
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381286 NCBI Gene Model | MGI Sequence Detail 7171 C57BL/6J ±  kb
transcript NM_201363 RefSeq | MGI Sequence Detail 1659 C57BL/6  
polypeptide NP_958751 RefSeq | MGI Sequence Detail 386 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 14
    cDNA 5
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:2447807, MGI:2447808
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory