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Tmem42 Gene Detail
Summary
  • Symbol
    Tmem42
  • Name
    transmembrane protein 42
  • Synonyms
    0610027O18Rik, 4933429E06Rik, D9Ertd662e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277176
    NCBI Gene: 66079
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:122850391-122852770 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 73.52 cM, cytoband F4
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    144 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277176
 protein coding gene Chr9:122850072-122852770 (+)
129S1/SvImJ ENSMUSG00200028146
 protein coding gene Chr9:119978060-119980439 (+)
A/J ENSMUSG00195026002
 protein coding gene Chr9:119118182-119120563 (+)
AKR/J ENSMUSG00220018696
 protein coding gene Chr9:119589616-119591995 (+)
BALB/cJ ENSMUSG00180025298
 protein coding gene Chr9:119658013-119660393 (+)
C3H/HeJ ENSMUSG00175017721
 protein coding gene Chr9:119894372-119896752 (+)
C57BL/6NJ ENSMUSG00215015663
 protein coding gene Chr9:119813181-119815560 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032851
 protein coding gene Chr9:118351781-118353898 (+)
CAST/EiJ ENSTCUG00005016638
 protein coding gene Chr9:119482632-119485011 (+)
CBA/J ENSMUSG00210034935
 protein coding gene Chr9:119617835-119620214 (+)
DBA/2J ENSMUSG00185015173
 protein coding gene Chr9:119953490-119955869 (+)
FVB/NJ ENSMUSG00205022883
 protein coding gene Chr9:119784755-119787136 (+)
JF1/MsJ ENSUMUG00000044662
 protein coding gene Chr9:119750949-119753358 (+)
LP/J ENSMUSG00230034711
 protein coding gene Chr9:120118204-120120583 (+)
NOD/ShiLtJ ENSMUSG00190014455
 protein coding gene Chr9:119561082-119563461 (+)
NZO/HlLtJ ENSMUSG00225023522
 protein coding gene Chr9:120378520-120380899 (+)
PWK/PhJ ENSLUMG00010034201
 protein coding gene Chr9:119647954-119650371 (+)
SPRET/EiJ ENSMSPG00010000449
 protein coding gene Chr9:121370822-121373236 (+)
WSB/EiJ ENSIUOG00005020326
 protein coding gene Chr9:118988680-118991044 (+)



Homology
more
  • Human Ortholog
    TMEM42, transmembrane protein 42
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM42, transmembrane protein 42
  • Links
    NCBI Gene ID: 131616
    UniProt: Q69YG0

  • Chr Location
    3p21.31; chr3:44861889-44865670 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000066233 Ensembl Gene Model | MGI Sequence Detail 2380 C57BL/6J ±  kb
    transcript ENSMUST00000084733 Ensembl | MGI Sequence Detail 1041 Not Applicable  
    polypeptide ENSMUSP00000081784 Ensembl | MGI Sequence Detail 157 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 8
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1913329, MGI:1918523, MGI:2143245
    References
    more
    • Summaries
      All 30
      Gene Ontology 1
      Phenotypes 6
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory