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Reep5 Gene Detail
Summary
  • Symbol
    Reep5
  • Name
    receptor accessory protein 5
  • Synonyms
    Dp1, DP1/TB2, TB2/DP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1270152
    NCBI Gene: 13476
  • Alliance
    genome feature page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:34477938-34507123 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 18.57 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    952 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1270152
 protein coding gene Chr18:34477938-34508044 (-)
129S1/SvImJ ENSMUSG00200042881
 protein coding gene Chr18:31478477-31507654 (-)
A/J ENSMUSG00195033621
 protein coding gene Chr18:31640943-31670141 (-)
AKR/J ENSMUSG00220017000
 protein coding gene Chr18:31619136-31648331 (-)
BALB/cJ ENSMUSG00180016895
 protein coding gene Chr18:32090632-32119829 (-)
C3H/HeJ ENSMUSG00175032742
 protein coding gene Chr18:31591676-31620855 (-)
C57BL/6NJ ENSMUSG00215012546
 protein coding gene Chr18:31346310-31375505 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022087
 protein coding gene Chr18:31598534-31626653 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210021159
 protein coding gene Chr18:31632809-31662007 (-)
DBA/2J ENSMUSG00185018144
 protein coding gene Chr18:31567407-31596600 (-)
FVB/NJ ENSMUSG00205018722
 protein coding gene Chr18:31286219-31315410 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230045281
 protein coding gene Chr18:33675306-33704481 (-)
NOD/ShiLtJ ENSMUSG00190020602
 protein coding gene Chr18:31345442-31374629 (-)
NZO/HlLtJ ENSMUSG00225043762
 protein coding gene Chr18:33577949-33607135 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    REEP5, receptor accessory protein 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    REEP5, receptor accessory protein 5
  • Synonyms
    C5orf18, D5S346, DP1, POB16, TB2, Yip2e, YOP1
  • Links
    NCBI Gene ID: 7905
    UniProt: Q00765

  • Chr Location
    5q22.2; chr5:112876385-112922328 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Mice homozygous for a gene trap insertion exhibit no detectable mutant phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    23
  • cDNA Data
    187
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000005873 Ensembl Gene Model | MGI Sequence Detail 29186 C57BL/6J ±  kb
transcript ENSMUST00000006027 Ensembl | MGI Sequence Detail 2852 Not Applicable  
polypeptide ENSMUSP00000006027 Ensembl | MGI Sequence Detail 189 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 192
    Genomic 2
    cDNA 187
    Primer pair 3

    Microarray probesets 7
Other
Accession IDs
less
MGI:2147209, MGI:2147316, MGI:2147366, MGI:2147419
References
more
  • Summaries
    All 47
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:28299 Kawai J, et al., Correspondence of RLGS-M spot behavior with tissue expression on mouse homologue of DP1/TB2 gene. Biochem Biophys Res Commun. 1995 Aug 24;213(3):967-74
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory