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Cyp2j6 Gene Detail
Summary
  • Symbol
    Cyp2j6
  • Name
    cytochrome P450, family 2, subfamily j, polypeptide 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1270148
    NCBI Gene: 13110
  • Member of
    Cyp2j cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:96404375-96441898 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 44.62 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1145 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1270148
 protein coding gene Chr4:96404375-96449835 (-)
129S1/SvImJ ENSMUSG00200009822
 protein coding gene Chr4:91380161-91417684 (-)
A/J ENSMUSG00195008254
 protein coding gene Chr4:91908107-91945621 (-)
AKR/J ENSMUSG00220019269
 protein coding gene Chr4:91365568-91403059 (-)
BALB/cJ ENSMUSG00180005949
 protein coding gene Chr4:90853648-90891167 (-)
C3H/HeJ ENSMUSG00175007460
 protein coding gene Chr4:91845638-91883154 (-)
C57BL/6NJ ENSMUSG00215012421
 protein coding gene Chr4:91775174-91812701 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005018587
 protein coding gene Chr4:91123511-91161018 (-)
CBA/J ENSMUSG00210016074
 protein coding gene Chr4:91369448-91406964 (-)
DBA/2J ENSMUSG00185021360
 protein coding gene Chr4:92180245-92217764 (-)
FVB/NJ ENSMUSG00205013499
 protein coding gene Chr4:90380207-90417726 (-)
JF1/MsJ ENSUMUG00000033941
 protein coding gene Chr4:92269325-92306803 (-)
LP/J ENSMUSG00230018433
 protein coding gene Chr4:95489131-95526650 (-)
NOD/ShiLtJ ENSMUSG00190016656
 protein coding gene Chr4:90845563-90883053 (-)
NZO/HlLtJ ENSMUSG00225002484
 protein coding gene Chr4:100633054-100670587 (-)
PWK/PhJ ENSLUMG00010003356
 protein coding gene Chr4:89984967-90022422 (-)
SPRET/EiJ ENSMSPG00010008003
 protein coding gene Chr4:92185232-92221959 (-)
WSB/EiJ ENSIUOG00005012417
 protein coding gene Chr4:91176850-91214278 (-)



Homology
more
  • Human Ortholog
    CYP2J2, cytochrome P450 family 2 subfamily J member 2
  • Vertebrate Orthologs
    13
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2J2, cytochrome P450 family 2 subfamily J member 2
  • Synonyms
    CPJ2, CYPIIJ2
  • Links
    NCBI Gene ID: 1573
    UniProt: P51589

  • Chr Location
    1p32.1; chr1:59893308-59969212 (-)  GRCh38
Human Diseases
more
  • Diseases
    5 with human CYP2J2 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    814
  • Tissues
    138
  • cDNA Data
    26
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052914 Ensembl Gene Model | MGI Sequence Detail 37524 C57BL/6J ±  kb
transcript ENSMUST00000030303 Ensembl | MGI Sequence Detail 3605 Not Applicable  
polypeptide ENSMUSP00000030303 Ensembl | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    cDNA 28
    Primer pair 2
    Antibodies 2

    Microarray probesets 4
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:47555 Ma J, et al., Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4. Genomics. 1998 Apr 1;49(1):152-5
  • Latest
    J:321481 Sisignano M, et al., Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12544-12549
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory