Cdkn2aipnl Gene Detail

Summary

• Symbol
  Cdkn2aipnl
• Name
  CDKN2A interacting protein N-terminal like
• Synonyms
  A430101B06Rik, D11Ertd497e

• Feature Type
  protein coding gene
• IDs
  MGI:1261797
  NCBI Gene: 52626
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr11:51858488-51868161 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 31.78 cM
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  35 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1261797	protein coding gene	Chr11:51858458-51868163 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018278	protein coding gene	Chr11:51250733-51260418 (+)
A/J	MGP_AJ_G0018247	protein coding gene	Chr11:49308712-49318654 (+)
AKR/J	MGP_AKRJ_G0018217	protein coding gene	Chr11:50856673-50866366 (+)
BALB/cJ	MGP_BALBcJ_G0018218	protein coding gene	Chr11:49605469-49615193 (+)
C3H/HeJ	MGP_C3HHeJ_G0018029	protein coding gene	Chr11:50897216-50906741 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0018668	protein coding gene	Chr11:52783818-52795376 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016320	protein coding gene	Chr11:46861894-46871502 (+)
CAST/EiJ	MGP_CASTEiJ_G0017594	protein coding gene	Chr11:50894205-50903400 (+)
CBA/J	MGP_CBAJ_G0018004	protein coding gene	Chr11:55277423-55287111 (+)
DBA/2J	MGP_DBA2J_G0018111	protein coding gene	Chr11:49010028-49019820 (+)
FVB/NJ	MGP_FVBNJ_G0018106	protein coding gene	Chr11:48734102-48743709 (+)
LP/J	MGP_LPJ_G0018187	protein coding gene	Chr11:51659751-51670275 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018129	protein coding gene	Chr11:56669050-56681556 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018711	protein coding gene	Chr11:50959392-50969125 (+)
PWK/PhJ	MGP_PWKPhJ_G0017369	protein coding gene	Chr11:49544622-49553808 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017164	protein coding gene	Chr11:50693728-50703218 (+)
WSB/EiJ	MGP_WSBEiJ_G0017641	protein coding gene	Chr11:50611189-50622112 (+)

Homology

• Human Ortholog
  CDKN2AIPNL, CDKN2A interacting protein N-terminal like

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CDKN2AIPNL, CDKN2A interacting protein N-terminal like
  
• Synonyms
  C2AIL
• Links
  HGNC:30545

  NCBI Gene ID: 91368

  neXtProt AC: NX_Q96HQ2

  UniProt: Q96HQ2

  
  
• Chr Location
  5q31.1; chr5:134402065-134411881 (-)  GRCh38

---

• Alliance of Genome Resources
  Cdkn2aipnl stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: CDKN2AIPNL
• Gene Tree
  Cdkn2aipnl
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  11 phenotype references
  

• All Mutations and Alleles
  10
• Chemically induced (other)
  1
• Endonuclease-mediated
  2
• Gene trapped
  4
• Targeted
  3
• Genomic Mutations
  1 involving Cdkn2aipnl
• Find Mice (IMSR)
  9 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  91

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase cdkn2aipnl

Interactions

• Cdkn2aipnl interacts with 189 markers (Mir1b, Mir7-1, Mir7-2, ...) View All

Sequences &
Gene Models

• All Sequences
  49
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS24663.1

• Ensembl
  ENSMUSG00000020392 (Evidence)
• NCBI Gene
  52626

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000020392	Ensembl Gene Model | MGI Sequence Detail	9674	C57BL/6J
transcript	ENSMUST00000102763	Ensembl | MGI Sequence Detail	1832	Not Applicable
polypeptide	ENSMUSP00000099824	Ensembl | MGI Sequence Detail	116	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000005277 CDKN2AIP N-terminal-like protein
  (term hierarchy)
• InterPro Domains
  IPR021859 XRN2-binding (XTBD) domain

Molecular
Reagents

• All nucleic 92

  cDNA 91

  Primer pair 1

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:1925030, MGI:2143992

References

• Summaries
  All 35

  Phenotypes 11
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194

TSS for Cdkn2aipnl:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr101301	Chr11:51858476-51858536 (+)	18 bp