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Atp5f1c Gene Detail
Summary
  • Symbol
    Atp5f1c
  • Name
    ATP synthase F1 subunit gamma
  • Synonyms
    1700094F02Rik, Atp5c1, F1 gamma
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261437
    NCBI Gene: 11949
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:10060841-10085321 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 6.86 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    143 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1261437
protein coding gene Chr2:10060827-10085321 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025337
protein coding gene Chr2:7408316-7433151 (-)
A/J MGP_AJ_G0025314
protein coding gene Chr2:7074629-7099292 (-)
AKR/J MGP_AKRJ_G0025283
protein coding gene Chr2:7300446-7333338 (-)
BALB/cJ MGP_BALBcJ_G0025310
protein coding gene Chr2:7077044-7102167 (-)
C3H/HeJ MGP_C3HHeJ_G0025070
protein coding gene Chr2:7252956-7278825 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025752
protein coding gene Chr2:7599297-7623502 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023166
protein coding gene Chr2:6588190-6612674 (-)
CAST/EiJ MGP_CASTEiJ_G0024533
protein coding gene Chr2:7281969-7307431 (-)
CBA/J MGP_CBAJ_G0025049
protein coding gene Chr2:7907071-7936931 (-)
DBA/2J MGP_DBA2J_G0025181
protein coding gene Chr2:7006986-7032141 (-)
FVB/NJ MGP_FVBNJ_G0025143
protein coding gene Chr2:6948138-6972865 (-)
LP/J MGP_LPJ_G0025267
protein coding gene Chr2:7284344-7310286 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025175
protein coding gene Chr2:7887315-7915773 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025810
protein coding gene Chr2:7252541-7278142 (-)
PWK/PhJ MGP_PWKPhJ_G0024284
protein coding gene Chr2:6988562-7013575 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024084
protein coding gene Chr2:7241657-7266951 (-)
WSB/EiJ MGP_WSBEiJ_G0024603
protein coding gene Chr2:7346163-7372667 (-)



Homology
more
  • Human Ortholog
    ATP5F1C, ATP synthase F1 subunit gamma
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP5F1C, ATP synthase F1 subunit gamma
  • Synonyms
    ATP5C, ATP5C1, ATP5CL1
  • Links
    NCBI Gene ID: 509
    neXtProt AC: NX_P36542
    UniProt: P36542

  • Chr Location
    10p14; chr10:7788147-7807815 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 11949 NCBI Gene Model | MGI Sequence Detail 24481 C57BL/6J ±  kb
transcript NM_001112738 RefSeq | MGI Sequence Detail 1815 C57BL/6  
polypeptide Q91VR2 UniProt | EBI | MGI Sequence Detail 298 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000004455 ATP synthase subunit gamma, mitochondrial
  • InterPro Domains
    IPR000131 ATP synthase, F1 complex, gamma subunit
    IPR023632 ATP synthase, F1 complex, gamma subunit conserved site
    IPR035968 ATP synthase, F1 complex, gamma subunit superfamily
Molecular
Reagents
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  • All nucleic 452
    Genomic 1
    cDNA 451

    Microarray probesets 5
Other
Accession IDs
less
MGI:1923973
References
more
  • Summaries
    All 49
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 9
  • Earliest
    J:46849 Ichida M, et al., MyoD is indispensable for muscle-specific alternative splicing in mouse mitochondrial ATP synthase gamma-subunit pre-mRNA. J Biol Chem. 1998 Apr 3;273(14):8492-501
  • Latest
    J:301602 Li Y, et al., MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nat Commun. 2020 Sep 24;11(1):4837

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory