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Igdcc3 Gene Detail
Summary
  • Symbol
    Igdcc3
  • Name
    immunoglobulin superfamily, DCC subclass, member 3
  • Synonyms
    2810401C09Rik, Punc, WI-14920
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202390
    NCBI Gene: 19289
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:65048471-65093154 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 35.13 cM, cytoband D-E1
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    114 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202390
 protein coding gene Chr9:65048404-65094313 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034950
 protein coding gene Chr9:64845316-64893807 (+)
A/J MGP_AJ_G0034930
 protein coding gene Chr9:62670244-62714667 (+)
AKR/J MGP_AKRJ_G0034860
 protein coding gene Chr9:64139350-64186108 (+)
BALB/cJ MGP_BALBcJ_G0034923
 protein coding gene Chr9:62391975-62438643 (+)
C3H/HeJ MGP_C3HHeJ_G0034633
 protein coding gene Chr9:64663158-64708478 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035442
 protein coding gene Chr9:66623382-66671460 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032353
 protein coding gene Chr9:62313902-62360588 (+)
CAST/EiJ MGP_CASTEiJ_G0033954
 protein coding gene Chr9:64859413-64912267 (+)
CBA/J MGP_CBAJ_G0034604
 protein coding gene Chr9:68934781-68986914 (+)
DBA/2J MGP_DBA2J_G0034763
 protein coding gene Chr9:62445685-62491962 (+)
FVB/NJ MGP_FVBNJ_G0034705
 protein coding gene Chr9:61763482-61808785 (+)
LP/J MGP_LPJ_G0034846
 protein coding gene Chr9:65125536-65174839 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034747
 protein coding gene Chr9:70185843-70232857 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035464
 protein coding gene Chr9:64250903-64301375 (+)
PWK/PhJ MGP_PWKPhJ_G0033658
 protein coding gene Chr9:62632540-62679978 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033492
 protein coding gene Chr9:64521805-64574324 (+)
WSB/EiJ MGP_WSBEiJ_G0034067
 protein coding gene Chr9:64149512-64199348 (+)



Homology
more
  • Human Ortholog
    IGDCC3, immunoglobulin superfamily DCC subclass member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGDCC3, immunoglobulin superfamily DCC subclass member 3
  • Synonyms
    HsT18880, PUNC
  • Links
    NCBI Gene ID: 9543
    neXtProt AC: NX_Q8IVU1
    UniProt: Q8IVU1

  • Chr Location
    15q22.31; chr15:65327127-65378002 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    5
  • Targeted
    4
  • Genomic Mutations
    1 involving Igdcc3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    19 strains or lines available
Homozygotes for a gene trap mutation exhibit reduced performance on the rotarod, suggesting impaired cerebellar function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1028
  • Tissues
    188
  • cDNA Data
    17
  • Literature Summary
    13
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032394 Ensembl Gene Model | MGI Sequence Detail 44684 C57BL/6J ±  kb
transcript ENSMUST00000217371 Ensembl | MGI Sequence Detail 3183 Not Applicable  
polypeptide ENSMUSP00000149084 Ensembl | MGI Sequence Detail 813 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    Genomic 2
    cDNA 17
    Primer pair 5
    Other 3

    Microarray probesets 6
Other
Accession IDs
less
MGI:1330814, MGI:1917204, MGI:2143154
References
more
  • Summaries
    All 41
    Developmental Gene Expression 13
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:46645 Salbaum JM, Punc, a novel mouse gene of the immunoglobulin superfamily, is expressed predominantly in the developing nervous system. Mech Dev. 1998 Feb;71(1-2):201-4
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory