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Tmem106c Gene Detail
Summary
  • Symbol
    Tmem106c
  • Name
    transmembrane protein 106C
  • Synonyms
    D15Ertd405e, MGC:54819
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196384
    NCBI Gene: 380967
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:97862081-97868156 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 53.96 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    322 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196384
 protein coding gene Chr15:97862077-97868158 (+)
129S1/SvImJ ENSMUSG00200050231
 protein coding gene Chr15:95047775-95053754 (+)
A/J ENSMUSG00195039957
 protein coding gene Chr15:94894700-94900597 (+)
AKR/J ENSMUSG00220042511
 protein coding gene Chr15:94908219-94914246 (+)
BALB/cJ ENSMUSG00180044412
 protein coding gene Chr15:94836983-94843066 (+)
C3H/HeJ ENSMUSG00175033998
 protein coding gene Chr15:95074954-95080851 (+)
C57BL/6NJ ENSMUSG00215051246
 protein coding gene Chr15:94899872-94905955 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020218
 protein coding gene Chr15:91651830-91657632 (+)
CAST/EiJ ENSTCUG00005042013
 protein coding gene Chr15:94347326-94353245 (+)
CBA/J ENSMUSG00210026738
 protein coding gene Chr15:94867876-94873892 (+)
DBA/2J ENSMUSG00185034565
 protein coding gene Chr15:94907315-94913341 (+)
FVB/NJ ENSMUSG00205044461
 protein coding gene Chr15:94635031-94641114 (+)
JF1/MsJ ENSUMUG00000026913
 protein coding gene Chr15:94397116-94403053 (+)
LP/J ENSMUSG00230034821
 protein coding gene Chr15:98237932-98243963 (+)
NOD/ShiLtJ ENSMUSG00190034885
 protein coding gene Chr15:94914570-94920601 (+)
NZO/HlLtJ ENSMUSG00225041412
 protein coding gene Chr15:98535850-98542101 (+)
PWK/PhJ ENSLUMG00010048794
 protein coding gene Chr15:94558379-94564619 (+)
SPRET/EiJ ENSMSPG00010036691
 protein coding gene Chr15:96362254-96368145 (+)
WSB/EiJ ENSIUOG00005033982
 protein coding gene Chr15:94976812-94982791 (+)



Homology
more
  • Human Ortholog
    TMEM106C, transmembrane protein 106C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM106C, transmembrane protein 106C
  • Links
    NCBI Gene ID: 79022
    UniProt: Q9BVX2

  • Chr Location
    12q13.11; chr12:47963569-47968885 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    610
  • Tissues
    7
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052369 Ensembl Gene Model | MGI Sequence Detail 6076 C57BL/6J ±  kb
transcript ENSMUST00000229428 Ensembl | MGI Sequence Detail 1455 Not Applicable  
polypeptide ENSMUSP00000154819 Ensembl | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145941, MGI:2687015
References
more
  • Summaries
    All 48
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 24
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory