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Znrf2 Gene Detail
Summary
  • Symbol
    Znrf2
  • Name
    zinc and ring finger 2
  • Synonyms
    1190002C14Rik, D6Ertd365e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196246
    NCBI Gene: 387524
  • Alliance
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:54793901-54867209 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 27.15 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1540 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196246
protein coding gene Chr6:54793901-54870485 (+)
129S1/SvImJ ENSMUSG00200006048
protein coding gene Chr6:51770272-51846861 (+)
A/J ENSMUSG00195031424
protein coding gene Chr6:51507372-51583958 (+)
AKR/J ENSMUSG00220005078
protein coding gene Chr6:51203829-51280425 (+)
BALB/cJ ENSMUSG00180009705
protein coding gene Chr6:51801346-51877933 (+)
C3H/HeJ ENSMUSG00175038913
protein coding gene Chr6:51562481-51639066 (+)
C57BL/6NJ ENSMUSG00215017913
protein coding gene Chr6:51778640-51855234 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028407
protein coding gene Chr6:49289930-49366881 (+)
CAST/EiJ ENSTCUG00005004794
protein coding gene Chr6:51040474-51117559 (+)
CBA/J ENSMUSG00210033581
protein coding gene Chr6:51606866-51683451 (+)
DBA/2J ENSMUSG00185017378
protein coding gene Chr6:52186416-52262995 (+)
FVB/NJ ENSMUSG00205021775
protein coding gene Chr6:51836356-51912960 (+)
JF1/MsJ ENSUMUG00000032242
protein coding gene Chr6:51566143-51642112 (+)
LP/J ENSMUSG00230011717
protein coding gene Chr6:53267327-53343903 (+)
NOD/ShiLtJ ENSMUSG00190007940
protein coding gene Chr6:51518016-51594609 (+)
NZO/HlLtJ ENSMUSG00225013362
protein coding gene Chr6:55258906-55335499 (+)
PWK/PhJ ENSLUMG00010020877
protein coding gene Chr6:51313067-51388760 (+)
SPRET/EiJ ENSMSPG00010008697
protein coding gene Chr6:51914249-51984388 (+)
WSB/EiJ ENSIUOG00005019539
protein coding gene Chr6:51868998-51945815 (+)



Homology
more
  • Human Ortholog
    ZNRF2, zinc and ring finger 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNRF2, zinc and ring finger 2
  • Synonyms
    RNF202
  • Links
    NCBI Gene ID: 223082
    UniProt: Q8NHG8

  • Chr Location
    7p14.3; chr7:30284418-30370457 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 387524 NCBI Gene Model | MGI Sequence Detail 73309 C57BL/6J ±  kb
transcript NM_199143 RefSeq | MGI Sequence Detail 2610 ZRU/MplStud  
polypeptide Q71FD5 UniProt | EBI | MGI Sequence Detail 238 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 2
    cDNA 9
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
less
MGI:1916108, MGI:2141592
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory