Igf2os Gene Detail

Summary

• Symbol
  Igf2os
• Name
  insulin-like growth factor 2, opposite strand
• Synonyms
  Igf2as, Peg8

• Feature Type
  antisense lncRNA gene
  BioType Conflict
  
• IDs
  MGI:1195257
  NCBI Gene: 111975
• Alliance
  genome feature page
• Transcription Start Sites
  18 TSS

Location &
Maps

• Sequence Map
  Chr7:142213430-142224093 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 87.99 cM
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  184 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1195257	antisense lncRNA gene	Chr7:142213417-142224093 (+)
129S1/SvImJ	ENSMUSG00200046799	lncRNA gene	Chr7:128779804-128790469 (+)
A/J	ENSMUSG00195041385	lncRNA gene	Chr7:133261863-133272527 (+)
AKR/J	ENSMUSG00220038056	lncRNA gene	Chr7:126744089-126754749 (+)
BALB/cJ	ENSMUSG00180042399	lncRNA gene	Chr7:129953310-129963950 (+)
C3H/HeJ	ENSMUSG00175043311	lncRNA gene	Chr7:130682792-130693455 (+)
C57BL/6NJ	ENSMUSG00215048139	lncRNA gene	Chr7:129949127-129959794 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0004091	antisense lncRNA gene	Chr7:144863317-144874033 (+)
CAST/EiJ	ENSTCUG00005051076	lncRNA gene	Chr7:133251569-133262271 (+)
CBA/J	ENSMUSG00210032734	lncRNA gene	Chr7:130440706-130451370 (+)
DBA/2J	ENSMUSG00185018671	lncRNA gene	Chr7:134719285-134729948 (+)
FVB/NJ	ENSMUSG00205047271	lncRNA gene	Chr7:130361406-130372070 (+)
JF1/MsJ	ENSUMUG00000050546	lncRNA gene	Chr7:139795381-139806065 (+)
LP/J	ENSMUSG00230043159	lncRNA gene	Chr7:140882619-140893282 (+)
NOD/ShiLtJ	ENSMUSG00190030931	lncRNA gene	Chr7:130548182-130558844 (+)
NZO/HlLtJ	ENSMUSG00225052859	lncRNA gene	Chr7:139091544-139102207 (+)
PWK/PhJ	ENSLUMG00010048427	lncRNA gene	Chr7:128923224-128933895 (+)
SPRET/EiJ	ENSMSPG00010044653	lncRNA gene	Chr7:130389970-130400649 (+)
WSB/EiJ	ENSIUOG00005037836	lncRNA gene	Chr7:131311440-131322121 (+)

Homology

• Human Ortholog
  IGF2-AS, IGF2 antisense RNA

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  IGF2-AS, IGF2 antisense RNA
  
• Synonyms
  IGF2AS, IGF2-AS1, PEG8
• Links
  HGNC:14062

  NCBI Gene ID: 51214

  
  
• Chr Location
  11p15.5; chr11:2140501-2148666 (+)  GRCh38

---

• MGI Vertebrate Homology
  Igf2os stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: IGF2-AS
• Gene Tree
  Igf2os
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  653
• Tissues
  15
• cDNA Data
  8
• Literature Summary
  5

Images

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  33
• RefSeq
  1
• UniProt
  2

• Ensembl
  ENSMUSG00000086266 (Evidence)
• NCBI Gene
  111975

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000086266	Ensembl Gene Model | MGI Sequence Detail	10664	C57BL/6J
transcript	ENSMUST00000141681	Ensembl | MGI Sequence Detail	4778	Not Applicable
polypeptide	A0A159ZPB9	UniProt | EBI | MGI Sequence Detail	149	Not Applicable

Protein
Information

• UniProt
  2 Sequences

Molecular
Reagents

• All nucleic 13

  Genomic 5

  cDNA 8

  
  

  Microarray probesets 3

References

• Summaries
  All 20

  Developmental Gene Expression 5

  Phenotypes 1
• Earliest
  J:14435 Rivkin M, et al., Identification of an antisense transcript from the IGF-II locus in mouse. Mol Reprod Dev. 1993 Aug;35(4):394-7
• Latest
  J:210271 Duart-Garcia C, et al., Functional expression study of igf2 antisense transcript in mouse. Int J Genomics. 2014;2014:390296

TSS for Igf2os:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr70241	Chr7:142212269-142212322 (+)	-1,134 bp
Tssr70242	Chr7:142212333-142212366 (+)	-1,080 bp
Tssr70243	Chr7:142212597-142212636 (+)	-813 bp
Tssr70244	Chr7:142212647-142212690 (+)	-761 bp
Tssr70245	Chr7:142212758-142212769 (+)	-666 bp
Tssr70246	Chr7:142212840-142212852 (+)	-584 bp
Tssr70247	Chr7:142212886-142212915 (+)	-529 bp
Tssr70248	Chr7:142212961-142212989 (+)	-455 bp
Tssr70249	Chr7:142214071-142214080 (+)	646 bp
Tssr70250	Chr7:142214191-142214196 (+)	764 bp
Tssr70251	Chr7:142214217-142214234 (+)	796 bp
Tssr70252	Chr7:142214314-142214321 (+)	888 bp
Tssr70253	Chr7:142214360-142214385 (+)	943 bp
Tssr70254	Chr7:142214391-142214404 (+)	968 bp
Tssr70255	Chr7:142214468-142214497 (+)	1,053 bp
Tssr70256	Chr7:142218866-142218894 (+)	5,450 bp
Tssr70257	Chr7:142219522-142219531 (+)	6,097 bp
Tssr70258	Chr7:142219540-142219557 (+)	6,119 bp