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Ablim1 Gene Detail
Summary
  • Symbol
    Ablim1
  • Name
    actin-binding LIM protein 1
  • Synonyms
    2210411C18Rik, 2610209L21Rik, 4833406P10Rik, 9330196J19Rik, abLIM-L, abLIM-M, abLIM-S, Limab1, mKIAA0059
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194500
    NCBI Gene: 226251
  • Alliance
    gene page
  • Transcription Start Sites
    35 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:57021165-57303351 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 52.09 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4118 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1194500
 protein coding gene Chr19:57021165-57303776 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025272
 protein coding gene Chr19:57421604-57725955 (-)
A/J MGP_AJ_G0025248
 protein coding gene Chr19:54585001-54872933 (-)
AKR/J MGP_AKRJ_G0025217
 protein coding gene Chr19:56308062-56599883 (-)
BALB/cJ MGP_BALBcJ_G0025243
 protein coding gene Chr19:54664317-54952846 (-)
C3H/HeJ MGP_C3HHeJ_G0025003
 protein coding gene Chr19:56543326-56833952 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025686
 protein coding gene Chr19:58800813-59096631 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023098
 protein coding gene Chr19:53507386-53789611 (-)
CAST/EiJ MGP_CASTEiJ_G0024468
 protein coding gene Chr19:56582651-56879018 (-)
CBA/J MGP_CBAJ_G0024983
 protein coding gene Chr19:61713487-62021991 (-)
DBA/2J MGP_DBA2J_G0025115
 protein coding gene Chr19:54366574-54648191 (-)
FVB/NJ MGP_FVBNJ_G0025076
 protein coding gene Chr19:54079783-54367202 (-)
LP/J MGP_LPJ_G0025201
 protein coding gene Chr19:57277493-57568266 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025109
 protein coding gene Chr19:60968791-61266497 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025744
 protein coding gene Chr19:56514116-56804556 (-)
PWK/PhJ MGP_PWKPhJ_G0024216
 protein coding gene Chr19:54338173-54624155 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024019
 protein coding gene Chr19:55194000-55500133 (-)
WSB/EiJ MGP_WSBEiJ_G0024538
 protein coding gene Chr19:56650883-56944531 (-)



Homology
more
  • Human Ortholog
    ABLIM1, actin binding LIM protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ABLIM1, actin binding LIM protein 1
  • Synonyms
    ABLIM, abLIM-1, LIMAB1, LIMATIN
  • Links
    NCBI Gene ID: 3983
    neXtProt AC: NX_O14639
    UniProt: O14639

  • Chr Location
    10q25.3; chr10:114431110-114801373 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Mutant mice lacking the retina-specific isoform are healthy, fertile, and show no defects in retinal development or retinofugal projections.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    19
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    850
  • Tissues
    70
  • cDNA Data
    25
  • Literature Summary
    14
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025085 Ensembl Gene Model | MGI Sequence Detail 282187 C57BL/6J ±  kb
transcript ENSMUST00000079360 Ensembl | MGI Sequence Detail 7152 Not Applicable  
polypeptide ENSMUSP00000078336 Ensembl | MGI Sequence Detail 861 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    17 Sequences
  • InterPro Domains
    IPR032402 Putative adherens-junction anchoring domain
    IPR003128 Villin headpiece
    IPR036886 Villin headpiece domain superfamily
    IPR001781 Zinc finger, LIM-type
Molecular
Reagents
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  • All nucleic 35
    Genomic 1
    cDNA 29
    Primer pair 3
    Other 2

    Microarray probesets 7
Other
Accession IDs
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MGI:1917386, MGI:1919728, MGI:2147671, MGI:2147702, MGI:2147721, MGI:2442818, MGI:2442960
References
more
  • Summaries
    All 50
    Developmental Gene Expression 14
    Gene Ontology 11
    Phenotypes 6
  • Earliest
    J:40509 Kim AC, et al., Limatin (LIMAB1), an actin-binding LIM protein, maps to mouse chromosome 19 and human chromosome 10q25, a region frequently deleted in human cancers. Genomics. 1997 Dec 1;46(2):291-3
  • Latest
    J:300948 Chen X, et al., QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function. Nat Commun. 2021 Jan 4;12(1):89
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory