About   Help   FAQ
Gsg1 Gene Detail
Summary
  • Symbol
    Gsg1
  • Name
    germ cell associated 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194499
    NCBI Gene: 14840
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:135214327-135231334 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 66.07 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1194499
 protein coding gene Chr6:135214324-135231349 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031417
 protein coding gene Chr6:139584630-139602780 (-)
A/J MGP_AJ_G0031393
 protein coding gene Chr6:134067794-134084776 (-)
AKR/J MGP_AKRJ_G0031320
 protein coding gene Chr6:138150136-138167122 (-)
BALB/cJ MGP_BALBcJ_G0031399
 protein coding gene Chr6:133903385-133923894 (-)
C3H/HeJ MGP_C3HHeJ_G0031121
 protein coding gene Chr6:138187712-138204728 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031859
 protein coding gene Chr6:143379113-143397162 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028991
 protein coding gene Chr6:133223230-133240811 (-)
CAST/EiJ MGP_CASTEiJ_G0030490
 protein coding gene Chr6:137629698-137646798 (-)
CBA/J MGP_CBAJ_G0031080
 protein coding gene Chr6:148712130-148729101 (-)
DBA/2J MGP_DBA2J_G0031238
 protein coding gene Chr6:132918995-132939222 (-)
FVB/NJ MGP_FVBNJ_G0031188
 protein coding gene Chr6:131842420-131859800 (-)
LP/J MGP_LPJ_G0031322
 protein coding gene Chr6:139662491-139684604 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031228
 protein coding gene Chr6:152727081-152744036 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031892
 protein coding gene Chr6:137910318-137928614 (-)
PWK/PhJ MGP_PWKPhJ_G0030215
 protein coding gene Chr6:131424803-131442588 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030039
 protein coding gene Chr6:136080325-136098237 (-)
WSB/EiJ MGP_WSBEiJ_G0030581
 protein coding gene Chr6:138536829-138555686 (-)



Homology
more
  • Human Ortholog
    GSG1, germ cell associated 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GSG1, germ cell associated 1
  • Links
    NCBI Gene ID: 83445
    neXtProt AC: NX_Q2KHT4
    UniProt: Q2KHT4

  • Chr Location
    12p13.1; chr12:13083532-13103683 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Male mice homozygous for a null allele exhibit normal fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    60
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14840 NCBI Gene Model | MGI Sequence Detail 17008 C57BL/6J ±  kb
transcript NM_010352 RefSeq | MGI Sequence Detail 1448 Not Specified  
polypeptide Q8R1W2 UniProt | EBI | MGI Sequence Detail 324 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    cDNA 60

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:21735 Tanaka H, et al., Isolation and characterization of cDNA clones specifically expressed in testicular germ cells. FEBS Lett. 1994 Nov 21;355(1):4-10
  • Latest
    J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory