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Kcns3 Gene Detail
Summary
  • Symbol
    Kcns3
  • Name
    potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
  • Synonyms
    D12Ertd137e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098804
    NCBI Gene: 238076
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:11140738-11201186 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 5.58 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    370 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098804
 protein coding gene Chr12:11140203-11201186 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019596
 protein coding gene Chr12:8277041-8337429 (-)
A/J MGP_AJ_G0019563
 protein coding gene Chr12:7976835-8039683 (-)
AKR/J MGP_AKRJ_G0019533
 protein coding gene Chr12:8494403-8558449 (-)
BALB/cJ MGP_BALBcJ_G0019538
 protein coding gene Chr12:8174308-8228616 (-)
C3H/HeJ MGP_C3HHeJ_G0019344
 protein coding gene Chr12:8296860-8356716 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019987
 protein coding gene Chr12:8557027-8629210 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017612
 protein coding gene Chr12:7690314-7800031 (-)
CAST/EiJ MGP_CASTEiJ_G0018900
 protein coding gene Chr12:8272656-8327584 (-)
CBA/J MGP_CBAJ_G0019315
 protein coding gene Chr12:9163575-9221531 (-)
DBA/2J MGP_DBA2J_G0019428
 protein coding gene Chr12:7949887-8005194 (-)
FVB/NJ MGP_FVBNJ_G0019419
 protein coding gene Chr12:7885804-7952987 (-)
LP/J MGP_LPJ_G0019499
 protein coding gene Chr12:8324967-8386480 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019452
 protein coding gene Chr12:8993940-9069720 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020026
 protein coding gene Chr12:8180199-8237917 (-)
PWK/PhJ MGP_PWKPhJ_G0018666
 protein coding gene Chr12:8048004-8102878 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018456
 protein coding gene Chr12:8265980-8322213 (-)
WSB/EiJ MGP_WSBEiJ_G0018951
 protein coding gene Chr12:8259986-8315929 (-)



Homology
more
  • Human Ortholog
    KCNS3, potassium voltage-gated channel modifier subfamily S member 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCNS3, potassium voltage-gated channel modifier subfamily S member 3
  • Synonyms
    KV9.3
  • Links
    NCBI Gene ID: 3790
    neXtProt AC: NX_Q9BQ31
    UniProt: Q9BQ31

  • Chr Location
    2p24.2; chr2:17877847-18361616 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    4
  • cDNA Data
    14
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 238076 NCBI Gene Model | MGI Sequence Detail 60449 C57BL/6J ±  kb
transcript NM_001413254 RefSeq | MGI Sequence Detail 2541 ZRU/MplStud  
polypeptide Q8BQZ8 UniProt | EBI | MGI Sequence Detail 491 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 2
    cDNA 14
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:314429 Miyamae T, et al., Kcns3 deficiency disrupts Parvalbumin neuron physiology in mouse prefrontal cortex: Implications for the pathophysiology of schizophrenia. Neurobiol Dis. 2021 Jul;155:105382
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory