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Clk3 Gene Detail
Summary
  • Symbol
    Clk3
  • Name
    CDC-like kinase 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098670
    NCBI Gene: 102414
  • Alliance
    gene page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:57657904-57672397 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 31.47 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    218 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098670
 protein coding gene Chr9:57657904-57673143 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034878
 protein coding gene Chr9:56988039-57002844 (-)
A/J MGP_AJ_G0034859
 protein coding gene Chr9:55140980-55156690 (-)
AKR/J MGP_AKRJ_G0034788
 protein coding gene Chr9:56411276-56434105 (-)
BALB/cJ MGP_BALBcJ_G0034851
 protein coding gene Chr9:54924130-54939010 (-)
C3H/HeJ MGP_C3HHeJ_G0034561
 protein coding gene Chr9:56895613-56911112 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035370
 protein coding gene Chr9:58572482-58589394 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032281
 protein coding gene Chr9:54445172-54460281 (-)
CAST/EiJ MGP_CASTEiJ_G0033882
 protein coding gene Chr9:56991182-57007516 (-)
CBA/J MGP_CBAJ_G0034532
 protein coding gene Chr9:60609384-60627069 (-)
DBA/2J MGP_DBA2J_G0034691
 protein coding gene Chr9:55005854-55021175 (-)
FVB/NJ MGP_FVBNJ_G0034633
 protein coding gene Chr9:54237031-54252033 (-)
LP/J MGP_LPJ_G0034774
 protein coding gene Chr9:57279357-57295849 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034676
 protein coding gene Chr9:62102489-62118094 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035392
 protein coding gene Chr9:56428700-56445430 (-)
PWK/PhJ MGP_PWKPhJ_G0033587
 protein coding gene Chr9:55044990-55060154 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033421
 protein coding gene Chr9:56711250-56726280 (-)
WSB/EiJ MGP_WSBEiJ_G0033995
 protein coding gene Chr9:56368580-56386056 (-)



Homology
more
  • Human Ortholog
    CLK3, CDC like kinase 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLK3, CDC like kinase 3
  • Synonyms
    PHCLK3, PHCLK3/152
  • Links
    NCBI Gene ID: 1198
    UniProt: P49761

  • Chr Location
    15q24.1; chr15:74598500-74645414 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    783
  • Tissues
    16
  • cDNA Data
    145
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 102414 NCBI Gene Model | MGI Sequence Detail 14494 C57BL/6J ±  kb
transcript NM_001410178 RefSeq | MGI Sequence Detail 3572 C57BL/6  
polypeptide O35492 UniProt | EBI | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 146
    cDNA 146

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143002
References
more
  • Summaries
    All 35
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:43003 Nayler O, et al., Characterization and comparison of four serine- and arginine-rich (SR) protein kinases. Biochem J. 1997 Sep 15;326(Pt 3):693-700
  • Latest
    J:256883 Zhou J, et al., Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory